Has anyone found a solution to counteract the side effect of anhedonia besides to come off of it? I've been on Tirzepatide for 5 months. I tried going down in dose but it has not subsided. Has @Anthony Castore ever addressed this?

@Anthony Castore In researching available exogenous options, I have come across one called Original Ketones by americanketone.com. It was mentioned by Dr. Ben Bikman on a podcast. Each bottle contains 80 grams of bioidentical BHB just like Kenetik Pro, except it costs quite a bit less per bottle. Do you have any thoughts pn this product by americanketone.com?

In the latest DDT Method podcast with @Anthony Castore , Anthony discussed NAD supplementation. What I found interesting is that Anthony seemed to be against NAD supplementation via NAD+ and its precursors if I understood correctly, and a more appropriate approach would be to instead use a combination of 5 amino and 1MNA. He suggested using 5 amino pre workout and 1MNA on rest days in the evening. Anthony - would you be able to expand on your thoughts regarding NAD supplementation given it seems like a given in the longevity community that you supplement with NAD+ (injection or IV) or its precursors (NMN, NR).

Hi Anthony, I recently saw this rodent study done by Ben Bikman's lab on BHB and 1,3 BD. https://www.mdpi.com/2072-6643/18/4/675 This study found: "1,3 BD induces significant hepatic stress characterized by ATP depletion, oxidative stress, and lipid accumulation. These results align with and extend recent findings by Ari and D’Agostino demonstrating formulation-dependent hepatic outcomes of chronic ketone supplementation, where ketone salts preserved liver health while BD-based ketone esters and precursors drove inflammation and steatosis" What are your thoughts on their findings? Does their study design bias the outcome? Are there similar studies that show that 1,3 BD is neutral in its effects? Does KineticPro or KE4 use ketones that are different than what was studied here? (It looks the same to my naive and uninformed eyes, so that's why I'm asking.)

Is there any difference between kenetic vs kenetic pro besides the amount of ketones? Are the tastes of the different flavors the same? When I calculate the per mg dose, the regular kenetic comes out to be a lot less expensive even when I use the discounted price that Anthony Castore offers through his buyers club. At higher doses, the Pro is more convenient, but not at a cost perspective.