How are we dosing glutathione?

@Anthony Castore I have a selfish question for a client of mine: how would you approach someone who has a hard time putting on muscle? For example: 6’1 22yo male, lean (but with a history or being overweight as a kid), and wants to be a bodybuilder. Blood work is good, test is 650-750 depending on season, behaviors and habits are in line with overall health and performance. Right now he’s taking spirulina+chlorella, BodyBio PC+Resolvin, Raw Materials (fulvic+humic acid), C60, SilverFern Postbiotic+ (l-lysine butyrate, BetaVita, Immuse), and glutathione. He’s still young, so I’m hesitant to start him on any enhancements, but he really wants to accelerate his progress (goal is IFBB Pro). We’re heading into a big growth season (spring/summer), so training and nutrition will be increasing soon to take advantage of the natural environment, as will lifestyle (lots of outside time under the sun). I just wanted to pick your brain a bit (if you’re okay with that), to see how you would think about the situation and what you believe are the limiting/underlying factors in someone who has trouble adding muscle mass. I really respect your knowledge and the ways you approach problems. I appreciate any response 🙏🏼

@Anthony Castore Hi, I’m looking for some guidance on a limited supplement protocol for my 84yo mother. A bit of her background- as stated, she’s 84 years young, has no major health issues; has sporadic cases of skin cancers on her face, had a kidney stone a few years ago, and has had a hip replacement, she doesn’t exercise (though up and about majority of the day everyday), does NOT pay attention to her lifestyle or nutrition (HEAVY carbohydrate intake), does not take any medications. It amazes me how “healthy” or at least symptom free she is when she does EVERYTHING wrong in terms of health and performance. She goes against just about everything I know and have learned and preach as a Health and Performance Consultant, which is wild to me haha shows how complex health truly is, and how much we still don’t understand Here’s what I’m thinking about having her take daily- omega 3s and spirulina+chlorella. To me, these will cover just about everything from a structural, pliability, immune, and deep nutritional aspect. I’m playing with either CLO or Resolvin from BodyBio (leaning towards Resolvin). Thoughts? The thing with the spirulina+chlorella is the amount of tabs needed daily (10+). She hates taking pills/capsules, so I also like the idea of using Human Potential (freeze dried bison organs). This way she could open the capsules and sprinkle the nutrients on her food or mix in her tea or whatever. I also really like, and would love for her to take would be C60 and PC from BodyBio. Giving her cells and membranes some direct love will obviously be hugely beneficial, but if I can only give her 2 things to focus on for now, I think omega 3s and a broad spectrum of nutrients, enzymes, peptides, and bioactives will cover more needs. Even sulforaphane for the Nrf, BDNF, etc… What do you think here? What would you change or add/swap? Obviously lifestyle and nutrition come first, but there is no chance I’m getting her to change those behaviors and habits at this point, so I want give her a few easy things to take daily to ensure her body/biology are being provided what they need so she can have a better health span at this point in her life and going forward. Thank you for any advice!

Hi, I know I posted this question in a response to another article, but it didn’t get a reply, so I’ll post it here and hopefully it’ll get a reply :) What can we do if we, or someone we know/work with, has a fish/shellfish allergy? The benefits of these food sources are unmatched and should be staples in our diet, but what if someone can’t eat them? Where should we start? Are we looking at alternatives? What would those alternatives even be? I know lamb is a good option for omega 3 content, but is it comparable? Spirulina + Chlorella are good here as well, but they’re non meat based, so it changes the equation. Are we looking at immune regulation? Exposure techniques? Gut focus? I know allergies stem from a dysfunction and mis/lack of communication between the immune systems (innate and adaptive), as well as from the skin-gut-immune-brain axis, so is getting circadian biology in rhythm over time and exposure the way to victory? Are there other ways to get these highly important molecules and nutrients into play with these kinds of individuals without consequences? I know Leviathan Nutrition has an ‘advanced omega’ product that uses lysine bound free fatty acid omega 3s along with sesamol to help package and deliver the omegas to appropriate tissues. Is this a viable option even for individuals with allergies? I’d believe so because the omegas are removed from the fish and in a different form, but could that also take away or not be such a great thing since it’s further from how nature intended? Or is there something in omega 3s inherently that would still cause a reaction? @Anthony Castore

Most people think of seafood as “protein plus omega-3s.” That framing is incomplete. What actually makes marine foods unique is not just the fats they contain, but how those fats are organized inside membranes. This organization happens through phospholipids, and phospholipids determine how cells breathe, signal, contract, recover, and adapt. If you want to understand muscle performance, brain health, recovery, inflammation, or aging, you have to understand membrane biology first. This article will walk through what phospholipids are, why membranes matter more than isolated nutrients, and how mussels, mackerel, sardines, and anchovies differ at a molecular level. We’ll move from beginner-friendly analogies to mitochondrial signaling and redox chemistry, and end with clear takeaways for clinicians and strength coaches. Start with a simple picture. Every cell in your body is wrapped in a membrane. Every mitochondrion inside that cell is also wrapped in membranes. These membranes are not passive walls. They are active, dynamic surfaces where energy transfer, signaling, and adaptation happen. The material those membranes are made of determines whether signals flow cleanly or break down into noise. Phospholipids are the structural units of membranes. Each phospholipid has a “head” that interacts with water and “tails” that interact with fat. When billions of them line up, they form a flexible, semi-fluid surface that proteins, receptors, enzymes, and ion channels embed into. If the phospholipid composition is poor, those proteins still exist, but they don’t work properly.A useful analogy is a racetrack. The engines (mitochondria) and drivers (enzymes) matter, but if the track surface is cracked or unstable, performance suffers no matter how strong the engine is. Phospholipids are the track surface. There are several major classes of phospholipids relevant to human physiology. Phosphatidylcholine (PC) provides membrane structure and transport. Phosphatidylethanolamine (PE) contributes to curvature and mitochondrial dynamics. Phosphatidylserine (PS) is critical for signaling, especially in neurons and muscle activation. Then there are plasmalogens, a special subclass with a unique chemical bond that gives them antioxidant and redox-buffering properties.