One of the most common cold email mistakes I see:
Pulling the plug on a campaign at 48 hours because the numbers look flat.
Here's the problem. Email stats don't mature that fast.
Open rates, reply rates, and bounce data take time to stabilize, sometimes 5-7 days depending on your send volume and how your list is distributed across timezones.
When you rewrite your copy at the 48-hour mark, you're making a decision based on noise, not signal. Then when things improve, you credit the new copy. But you probably just needed to wait.
Give your campaigns at least a week before making any changes. Judge on reply rate and positive reply rate, not opens. And resist the urge to optimize in real time.
The campaigns that work are usually the ones you left alone long enough to get real data.