Hello, I hope everyone is enjoying there thanksgiving today. I was curious to see what everyone thought about nicotine? I have used it in some of the troscription products and enjoyed the mental and sometime physical lift that gives me. (It is combined with methylene blue, caffiene and CBD in in that preperation however.) The more research i do on it, the more i realize what a bad wrap it has gotten, and what benefits it actuall offers to the user. Anyway, would love to hear people thoughts on the topic, and what dosage you use if you use it? Thanks

Last night, I woke up to something that shook me in a way I haven’t felt in a long time. My bulldog Jeter, who’s ten now and basically my shadow, was shivering on the inhale while he slept. At first I thought maybe he was cold, or dreaming. Bulldogs dream with their whole soul, so that wasn’t unusual. But something felt off. The tremor wasn’t rhythmic like dreaming. It was sharp, almost like a nerve misfiring. When he got up from bed to walk to another room, he seemed weak like his legs weren’t receiving the normal signals from his brain. His shoulders and legs trembled slightly, his paws looked unsure beneath him, and he kept repositioning like he couldn’t get comfortable. That’s when my stomach dropped. I scooped him up, put him in the car, and Julie and I drove straight to MedVet. If you’ve ever loved a dog deeply, you know that feeling where you go from half-asleep to wide awake with one single thought: “Please let him be okay.” At MedVet they gave him a ketamine and methadone shot for pain, and they suspected a disc issue in his spine. They didn’t run an MRI that night, so we were left with the kind of diagnosis most dog owners get at first: “Likely disc compression, monitor closely.” In other words, an entire universe of things could be happening under the surface. When we finally got back home, Jeter was sedated, wobbly, and tremoring. He was trying to be strong bulldogs have a level of pride that honestly rivals ours—but he was struggling. And in moments like that, both as a practitioner and as a dog dad, you are forced to sit between two worlds: the scientific understanding of what’s happening, and the emotional weight of watching someone you love suffer. That’s what inspired me to write this for you today not just to share the story, but to teach you what’s actually going on inside a dog’s body when a disc bulges, why the symptoms show up the way they do, and how targeted regenerative peptides like Pentosan, ARA-290, TB-500, BPC-157, and SS-31 can create a powerful recovery pathway when used correctly.

Almond milk is often marketed as a clean, healthy alternative to dairy, but most people don’t realize how far the store-bought version drifts from that image. Commercial almond milk is usually made with two percent almonds or less, which means an entire gallon contains only about one to one and a half ounces of actual almonds, roughly ten to fifteen nuts in total. That tiny amount of almond material is nowhere close to the nutrient density people expect. Whole almonds provide vitamin E, magnesium, polyphenols, healthy fats, protein, and fiber, but almost none of that survives the industrial milk-making process. What you end up drinking is mostly water, sweeteners, thickeners, and synthetic vitamins that create the illusion of nutrition rather than providing real nutrient density. Another piece people rarely hear about is the quality of the almonds used. The whole, beautiful, uniform almonds you find in grocery store bags are grade-A nuts. Those do not go into almond milk production. Manufacturers use what are considered subgrade almonds broken, discolored, insect-damaged, or aged nuts that didn’t make the cut for consumer shelves. These fragments may have been sitting in storage longer, may be partially oxidized, and sometimes have higher risk of mold exposure or poor handling. Since consumers never see the almonds in the final beverage and the taste is masked with vanilla or sweeteners, producers use the cheapest raw materials possible and rely on additives to fill in the gaps. The agricultural side is also more complicated than people think. Almonds are one of the most heavily sprayed crops in the United States, especially in California where most almonds are grown. The orchards are commonly treated with herbicides like glyphosate, pesticides such as chlorpyrifos, imidacloprid, and other neonicotinoids, and fungicides like propiconazole. Several of these chemicals are systemic, meaning they move into the plant tissue itself rather than remaining on the outer surface. Because commercial almond milk production doesn’t involve washing or peeling in the way consumers wash fresh produce, and because pasteurization does not remove chemical residues, those contaminants can remain present in the nuts used for milk. When you combine heavy pesticide use with the reliance on the lowest-quality almonds, the final product can contain more undesirable residues than most people would ever guess.

Anyone have experience with Cagrilintide? Either alone or stacked with a GLP1?

I've seen increasingly more references to injectable 5-amino-1mq. The dosages seem to be more along the lines of 150mcg-300mcg whereas many of the pill forms are 25mg-50mg. For @Anthony Castore I have 3 three questions: 1) Have you seen a way to equate dosages between oral form and subcutaneous injection to help determine what dosages correspond to each form? ie is 150mcg injectable similar to 25mcg oral? I know there are quite a few variables with oral bioavailability, but assuming taken fasted, and "normal" metabolism/uptake by the person how would the 2 forms equate? 2) is there any potential difference in mechanism of action or overall effect once dosages are equated? I assume time for effect is much faster for injection vs. oral, even when fasted 3) As an NNMT inhibitor, would you time 1-MNA with 5-amino-1mq or at an alternate time or day? Assume daily intake of 1-MNA already for sake of argument.