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Castore: Built to Adapt
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30 contributions to Castore: Built to Adapt
Mar 12 •Â
Feeling on 5Amino?
Just curious, other than looking for changes in the mirror, are there any other indicators that would tell me it’s working? I only ask because on SLU I felt a noticeable difference in my endurance during cardio sessions… On Tirz, my appetite tanks… Beta Alanine makes the fingers tingle.. Know what I’m sayin? A
0 likes • 10d
If you are not low on NAD you'll see no benefits. So many compounds aren't useful to a specific individual.. True: ok to experiment, but don't be dissapointed. Good luck curt
Jan 31 •Â
FINESTIN
I was watching a pod cast where the podcaster was talking about mega dosing this a couple times a year to get rid of senecese cells. Does anyone have experience with this or know if it is a real functional option. I just read an old article by Anthony o er on Chris Duffins endless evolution about layering Foxo4 Dri amd other peptides. Really enjoyed the article
1 like • 10d
@David Wood common protocols for senolytics: 3-5 days on 1-1.5 gr fisetin, often adding 1mg/day fox04-dri, many common add-ons are quercetin, grape seed extract, adding CTC clearing, circ tumor cells adding on either anti biotic: doxicycline or azermyacin at STD daily dosing. I agree this total is severe especially bthe antibiotics. Just reporting. Search Amazon theres the common nutricals all packaged up. Just 4-10 pills dep on brand. If older I agree with this. Ie over 50-60.. Curt
Mar 13 •Â
Vesilute peptide
Has anyone here tried the Vesilute peptide? I have had bladder issues since transitioning to menopause and I am thinking of trying it.
0 likes • 15d
@Nicola Lewis Great to hear Nicola!!! Folks need their base line blood work earlier and earlier due to stress, toxics in food, water and taking performance enhancing compounds. Just a thought that you get a full blood test regardless. The above is cheapest I've found, drawn at quest. Just have to add on DHT and progesterone since they are missing i the full female test (and the male test). Good luck, curt
0 likes • 15d
@Nicola Lewis BTW one of the vascular builders that is often overlooked is Vit K but MK4 not so much MK7. MK4 is food sourced and highest concentration is in of all things EMU oil. We take; https://nourishingworld.com/products/walkabout-emu-oil Often combined with vit D3 and vit A. A reasonable approach would be a combo called DAKE plus the Emu oil for MK4 add: https://www.amazon.com/dp/B0D5MPY6DV curt
Oct '25 •Â
NAD Supplementation
In the latest DDT Method podcast with @Anthony Castore , Anthony discussed NAD supplementation. What I found interesting is that Anthony seemed to be against NAD supplementation via NAD+ and its precursors if I understood correctly, and a more appropriate approach would be to instead use a combination of 5 amino and 1MNA. He suggested using 5 amino pre workout and 1MNA on rest days in the evening. Anthony - would you be able to expand on your thoughts regarding NAD supplementation given it seems like a given in the longevity community that you supplement with NAD+ (injection or IV) or its precursors (NMN, NR).
0 likes • Mar 21
@Damian Perez tnx ya so far single source. Found a 10% discount code, welcome Bought subscription... 🤣. Typical $30/mo is now $80... 😂😂😂
0 likes • 18d
@Joaquin Rodriguez https://ohphealth.com/products/endoteliol-1mna
1 like • Feb 27
But some say per Anton inferred, to dose with glutathion only when sick or some low point. If healthy and eating well, taking modest precursors, NAC, Glucine etc, no need normally.
0 likes • 19d
@Rob Taylor IMHO like injecting / IV NAD, glutatione has a narrower best use case then Bro's just injecting willy nilly. Theres negatives with shutting down ones endogenous glut production. But injecting 500mg of Test is not uncome either. I belive Anton was trying to be helpful. I'm not being quipe but trying to stick to what actually works health wise. I have a stash of injectable Glut as well but don't do it unless I'm sick as a dog and even then I suspect Anthonie would have more helpful timing inputs. Best to all, curt
1-10 of 30
@curtis-smith-7832
72yro male, 164#, 5'10", 31" waist, healthy, active, poly-nutricals, rapamycin 4yr, SGLT-2 etc, anti-aging / health span interests. Atlanta Georgia.
Active 8h ago
Joined Dec 26, 2025
Atlanta, Georgia, USA
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