I believe it was Stanley Jacob, DMSO pioneer, who used DMSO or DMSO/Water combination as the ultrasound coupling agent. He found it worked better with ultrasound. There is some research literature on this, e.g. https://pubmed.ncbi.nlm.nih.gov/19900747/ Has anybody had experience doing this? I'm especially thinking about whether repeated DMSO contact is compatible with the complete US Pro 2000 applicator. Any experience appreciated.

I want to learn more about the Vagus Nerve, I am glad to find this group.

does anyone here have the small circle / dot appear on their 2000 head, if so is this a defective device or just use and age?

Ok, so awhile back there was some discussion about safety regarding using the US-1000 / US-2000 devices for transcranial treatment on twitter / X. I think this may have arisen due to lack of accurate data on the power levels of these devices listed specs. I ordered my US-1000 from Tenspros. When I look at their listings, there is possibly some inaccurate power specs for the US-1000 IMO. I would like to get some feedback / clarification on this if possible. US-1000 Specs from tenspros: Product Specifications: - Power Source: AC Adapter - 100-240 Volts AC Input (DC 15V) - Frequency: 1.0 MHz ± 10% - ERA Treatment Area: 6.16 cm² ± 20% - Temporal Maximum Power: 4W ± 20% - Output Mode: Pulse - Output Intensity: 1.6W/cm² (Low), 2.6W/cm² (Medium), 4.6W/cm² (High) - Duty Cycle: 8% (Low), 14% (Medium), 29% (High) - Pulse Width:Low: 8% 0.5mS ± 10%Medium: 14% 1mS ± 10%High: 29% 2mS ± 10% - Repetition Rate: 150Hz ± 10% - Working Time: 30 Minutes - Material of Applicator: Aluminum - Beam Type: Collimated US-2000 Specs from tenspros: Product Specifications: - Ultrasound Modulation/Acoustic Frequency: 1.0 MHz ±10% - Temporal Maximum Output Power: 6.4W ± 20% (Modulation duty cycle at 100%) - Output Power:(L) 0.32W ± 20%(M) 3.20W ± 20%(H) 6.40W ± 20% - Pulse Repetition Rate: 100Hz ± 10% - Modulation Duty Cycle (Duty Factor): (L) 5%, (M) 50%, (H) 100% - Effective Radiating Area (ERA): 4.0 cm² ± 20% - Beam Non-uniformity Ratio (BNR): 5.0 max - Max. Effective Intensity: 1.6 W/cm² ± 20% (Modulation duty cycle at 100%) - Effective Intensity:(L) 0.08 W/cm² ± 20%(M) 0.80 W/cm² ± 20%(H) 1.60 W/cm² ± 20% - Treatment Time: 5, 10, or 15 minutes - Preheat Time: 3-5 minutes - Wave Form: Pulsed or Continuous - Dimensions: 7.95" L x 1.93" W x 2.76" H (202 x 49 x 70mm) - Weight: 0.43 lbs (193g) (without adapter) - Material of Applicator: Aluminum - Beam Type: Collimated There seems to be a discrepancy in the Output intensity for the US-1000, whereas the US-2000 listings seem accurate, IMO. The US-1000 peak power output is lower, yet it's low, medium output power is listed as follows:

The internal geometry of a 3D-printed conduit, such as the Nemuri Pendant, modulates respiratory resistance to induce a parasympathetic shift without electronic intervention. By adding calibrated resistance to the airway, the device facilitates a reduction in respiratory rate to the 4–6 breaths per minute range. This specific frequency optimizes heart rate variability and maximizes vagal tone by extending the exhalation phase. The mechanism relies on fluid dynamics rather than firmware. As the user breathes through the tuned internal channel, the added load engages the diaphragm and throat muscles more deliberately. This engagement, combined with soft pressure feedback, triggers the diving reflex to lower the heart rate and suppress sympathetic arousal. Physical markers of this vagal activation typically manifest within 90 seconds. Users observe a softening of the periorbital muscles and a release of tension in the trapezius and levator scapulae. The shift is a direct result of lengthening the expiratory phase, which enhances the inhibitory influence of the vagal efferents on the sinoatrial node. A rhythm of 4-second inhalations and 6-second exhalations through this resistance provides a structured method for retraining baseline breathing patterns. Because the device requires no batteries or apps, it serves as a permanent analog interface for nervous system regulation. It is a tool for immediate recovery after high-cortisol events or for maintaining autonomic balance during daily transitions. https://www.frontiersin.org/articles/10.3389/fnhum.2018.00353/full https://pubmed.ncbi.nlm.nih.gov/21939457/ https://vagushub.com/nemuri