The Ketone Playbook: My Go-To Protocols + Live Q&A

Anthony Castore

Aug '25 (edited) • Ask Anthony Anything

🚀 Ketones = Game Changer.

This is the thread where I’ll drop my go-to ketone protocols ⚡️ and YOU can fire away with any questions.

💬 Comment your experiences, hacks, and questions below—let’s build the ultimate ketone resource together.

👀 Webinar coming soon… stay tuned.

Practical Dosing Blueprints

1.Pre-Workout Protocol (Performance & Focus)

Goal: Elevate ketones, buffer acidosis, support hydration & glucose supply.

Hydration: 500–750ml water + electrolytes (sodium 500–1000mg, potassium 200–400mg).
Bicarbonate: 0.3 g/kg sodium bicarbonate (~20g for 70kg athlete), dissolved in water. Take 90–120 min before session to minimize GI upset.
Trehalose (Carbohydrate): 15–25g as slow-release carb for sustained glycogen supply.
Ketone Ester (D-BHB/1,3-BD): 15–25ml (~7–12g KE) 10–15 min pre-warmup.

Effect: Dual-fuel system (glucose + BHB), reduced acidosis, enhanced mental focus .

2.Intra-Workout Endurance Protocol

Goal: Sustain metabolic efficiency, prevent bonk, extend time-to-exhaustion.

Every 60 min: Trehalose or isomaltulose: 20–30g (slow carb). Ketone Ester: 10–15ml (~5–7g KE).
Optional: electrolyte top-up (sodium/potassium).

Effect: Preserves glycogen, stabilizes glucose, sustains BHB 1–3 mM .

3.Post-Workout Recovery Protocol

Goal: Accelerate glycogen resynthesis, repair, and inflammation control.

Protein: 20–30g whey or EAAs.
Carbs: 40–60g high-GI glucose or maltodextrin.
Ketone Ester: 20–30ml (~10–15g KE), taken 30–45 min post-exercise (separate from carb/protein drink for maximal signaling).
Trehalose: Add 10–15g if training volume is very high or glycogen depleted.

Effect: 50% faster glycogen replenishment, stronger mTOR activation, reduced inflammation .

4.Sleep Recovery Protocol (Athletes)

Goal: Deep recovery, improve next-day performance.

Ketone Ester: 2.5–10ml (~1–5g KE) immediately before bed.
Optional: Magnesium glycinate/threonate for additional relaxation.

Note: High doses (20–50ml) were used in studies, but may cause “second wind.” Keep micro-dosed unless after extreme events .

5.Weight Loss / Metabolic Reset Protocol

Goal: Blunt hunger, improve fat oxidation, support fasting adherence.

Morning fasted: 5–10ml (~2.5–5g KE).
Delay food for 1–2h (or skip breakfast).
Black coffee/water only.

Effect: Suppresses appetite, maintains ketone energy, enhances fat loss signaling .

6.Travel / Jet Lag Protocol

Goal: Prevent fatigue, improve resilience while fasting during flights.

Pre-flight: 5ml (~2.5g KE).
During flight: 5ml every 2–3h (men); 2.5ml (women).
Upon landing: Final 5ml dose.

Effect: Maintains ketone levels, stabilizes energy, reduces jet lag fatigue .

7.Neuroprotective / Cognitive Support Protocol

Goal: Provide ketones for brain energy, especially in APOE4, mild cognitive impairment, or TBI.

Daily: 0.25–0.5 bottles/day (~15–30ml total, split into 2–3 doses).
Therapeutic use: Up to 1 bottle/day (~60ml), divided AM/PM.

Effect: Improves mitochondrial efficiency, reduces oxidative stress, provides alternative brain fuel .

Key Integration Rules

Stack smart: For recovery → Carbs + Protein + Ketones. For performance → Bicarbonate + Ketones + Trehalose.
Split doses: Above ~30ml at once, split to prevent rapid crash.
Monitor blood ketones: Aim for 1–3 mM during performance/recovery phases.
Caution with stimulants: Ketones amplify caffeine → start low.

Ordering information:

**Please have orders in by Wednesday. Orders will be placed Wednesday evening and generally expect 1 week turn around

KenetikPro Ketone Concentrate 3-Pack (3 Bottles)

3-Pack MSRP: $149.00

KenetikPro Case - 24 Bottles (8 Packs of 3 Bottles Each)

$994.00 USD

Case Quantity | Case Price | Case Discount

1-2 $994.00

3-9 $874.80

10+ $755.60

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