Started HRT (E patch oral P) in Aug 2025. Im in late peri/early menopause. I have increased E twice and decreased E once, P has stayed the same. The first 2 weeks I feel better and around the 2 week mark (with both increase and decrease) symptoms get intense that are hard to deal with (bad anxiety, panic attacks, increased heart rate). I have others also low/heavy mood, crying a lot, no energy/motivation, bleeding.. I don’t know what to do. Am I having a hard time adjusting, have I not stayed on a dose long enough, is my own hormones fluctuating too much, is HRT not working for me? I just want to feel better. My son is getting married in 3 months and I have missed out on so much already. 😢

Struggling with weight gain 😫 changed my diet to the Mediterranean Diet and joined the gym and instead of losing weight I'm gaining more. It's really getting to me. Is anyone else having the same problem?

I’ve gained about 15 pounds in 10 months. I eat approximately 2200-2500 calories, walk 10k-14k steps in a day, have a desk job, eat 150g of protein a day, 25-35g of fiber and mainly a whole food diet. I also strength train 3 times a week for about 45 minutes each. I’m on progesterone, and an every other day 1/2 pump of testosterone cream. My sleep has improved this past year but could also keep getting better. I’ve been managing my stress through meditation, breath work and sauna. I’ve cut high intensity cardio out for now. I’ve also recently been put on thyroid medication as my T3 and T4 have been a bit sluggish. I still can’t lose the weight and I’m losing my muscle definition 😩. What else can I do to get a handle on the fat gain and muscle loss?

I thought I was doing pretty good for the first 10 months when I started HRT. I was taking Estrodial patch and Prometrium Progesterone. Then my doc increased P and I instantly gained 10lbs in about 6 weeks. Then she increase my E and another 5lbs. I’ve gone back down in P and up E, then up P again (oral/vag) but no weight loss. This summer I was diagnosed with plantar fasciitis and after a steroid shot and meds I gained again. It’s harder to workout the same as I used to and I can’t wear my weighted vest anymore. Now it’s been 7 months and it’s a total of 25lbs. It’s been impossible to lose 1lb. I tried GLP-1 in Sept but the fatigue was too much so I stopped. I thought it could be thyroid related cuz I took meds as a kid but doc says labs are fine. I do have elevated reverse T3 and they found a goiter but Endocrinologist also says labs are fine. Docs won’t check my iodine, selenium, iron or ferritin. I also have hair loss. I’m going to have a hair test to see if that will help narrow down what’s going on with me. It’s been incredibly disappointing cuz I’ve done to much to keep my weight down through the years and been on HRT but now I have to start all over again and nothing works! Plus, I’m in CA so I can’t be a patient. I’d love any advice anyone has to share.