How are we dosing glutathione?

I was watching a pod cast where the podcaster was talking about mega dosing this a couple times a year to get rid of senecese cells. Does anyone have experience with this or know if it is a real functional option. I just read an old article by Anthony o er on Chris Duffins endless evolution about layering Foxo4 Dri amd other peptides. Really enjoyed the article

Not all muscle is created equal. And not all hypertrophy gets you closer to your goal. Most programs are built around chasing the pump or soreness, but that’s only one slice of the hypertrophy pie. To build a physique that performs, ages well, and adapts intelligently—you need to train across multiple cellular pathways, not just chase fatigue. This post is heavily inspired by the brilliant work of Kilo Strength Society and N1 Education, both of which are world-class resources for understanding the nuance of program design and refining your coaching skills at the cellular and biomechanical level. Let’s break it down. 1. Sarcoplasmic Hypertrophy — The Storage WarehousePathway: mTORC1 → glycolysis-driven volume → increased sarcoplasmic fluid and glycogenMechanism: Repeated submaximal effort depletes glycogen and increases cell volume. The muscle adapts by expanding the sarcoplasm (fluid + fuel space).Why this happens: Your body sees repeated energy demand and says, “I need more room to store fuel.” - Reps/Sets: 10–15 reps, 3–5 sets - Tempo: 2-0-2-0 - Rest: 30–60 sec - RIR: 0–1 - Special Methods: Myo-reps, drop sets, supersets Analogy: Think of this as upgrading the size of your warehouse—not the machinery inside. It looks big, but it doesn’t necessarily lift more. When to use it: Early hypertrophy phases, deloads, or during high-carb phases to enhance insulin sensitivity. 2. Myofibrillar Hypertrophy — The Machinery ItselfPathway: mTORC1 + satellite cell activation → increased actin/myosin densityMechanism: Heavy loads and high tension cause structural damage to contractile fibers, forcing the body to reinforce them with more protein.Why this happens: “This load is threatening structural integrity. Reinforce the scaffolding.” - Reps/Sets: 4–8 reps, 3–6 sets - Tempo: 3-1-X-1 - Rest: 2–3 min - RIR: 2–3 - Special Methods: Cluster sets, rest-pause, wave loading Analogy: This is upgrading the actual engines on your ship. It doesn’t look much bigger, but it pulls harder, faster, and longer.

What protocol do you follow to minimize jet lag, avoid drops in HRV, and improve sleep after traveling to a different time zone? @Anthony Castore

I've got some of this on hand and am planning to run it. I've seen online, and from friends, who use igf-1lr3 that they're pinning right before work out into the targeted muscle. During workout they'll experience huge pumps. However, I heard Anthony on one of the DDT Method podcasts saying to run peg-mgf immediately post work out and igf-1lr3 the next day. Can anyone help with the reasoning to run this one way over the other the other?