My girlfriend has endometriosis and pcos. I am looking for any protocols or information that may lead to healing. She has been diagnosed with intersistal cystitis as well. If anyone has experience with things that have helped them or someone they know, please share.

This community exists to correct a problem I see every day: smart, motivated people making avoidable mistakes because they are reacting to information instead of reasoning through it. Everything here is built around clear thinking, proper sequencing, and confident restraint. There are several ways to engage. Each one is designed for a different level of responsibility. The question is not whether to invest. The question is where you are right now. The Cellular Intelligence Circle For Orientation, Context, and Staying Current The Circle is where confusion gets resolved before it turns into action. This is the right place if you want to: - Understand emerging science without overreacting to it - Learn how decisions are actually weighed - Separate signal from noise - Avoid unnecessary intervention It is a content-first environment designed to compound over time. Membership provides access to a growing, curated body of work that functions as a reference library, not a feed to keep up with. Inside the Circle: - Peptide of the Month (mechanism, context, restraint) - Protocol and case reasoning breakdowns - Science article reviews focused on interpretation, not hype - Monthly live Q and A - Periodic synthesis webinars The Circle is not coaching. It is not protocol delivery. It is where judgment is built. Pricing - $79 per month - $219 for three months - $499 for twelve months This level is appropriate when your primary goal is orientation, understanding, and staying sharp. One-Time Consultations For Specific Decisions. Consultations exist for moments when a decision needs to be handled correctly. They focus on: - Identifying what actually matters - Removing unnecessary complexity - Clarifying what not to do Pricing - One hour consultation: $350 - One hour consultation with follow-up: $500 This option makes sense when a single decision needs careful thought. Ongoing Advisory Core For Continuity and Guardrails. This is for people who no longer want to think through complex decisions in isolation.

I was just wondering what everyone’s favorite non peptide,sarm, steroid supplement was. Heres mine

Question: Have you noticed ATX causing extreme lethargy in people? @Drew Donaldson talks about it, he said he hates the compound and I went up to 300 mg and got super lethargic and brain fog too. Thank you @Josh Large for sending this to me. Answer: Yes, I have noticed people reporting lethargy and brain fog, but what is being experienced is not ATX “causing” those effects in isolation. What you are describing is exactly what happens when redox state, timing, dose, lifestyle context, and signal balance are not respected. This is not a compound failure. It is a signaling and systems failure, and it is entirely predictable once you understand the underlying biology. At a cellular level, ATX strongly biases signaling toward AMPK activation. AMPK is the cell’s energy stress sensor. It turns on when ATP availability drops or when the cell is told that energy scarcity exists. When AMPK is activated, it suppresses energy-expensive processes, including mTOR-driven protein synthesis, growth, and repair, while increasing pathways involved in efficiency, substrate conservation, and survival. This is adaptive when the signal is brief, well-timed, and followed by recovery. It becomes maladaptive when the signal is strong, prolonged, or layered on top of an already stressed system. When someone pushes the dose to 300 mg, especially while under-eating, fasting, training hard, sleeping poorly, or operating under high psychological stress, the body is already leaning toward an energy-conservation state. Adding a strong AMPK signal on top of that tells the cell that energy scarcity is not temporary, but ongoing. The cell responds logically by reducing output. This includes lowering mitochondrial ATP throughput, decreasing neuronal firing rates, reducing neurotransmitter synthesis, and downshifting overall metabolic demand. Subjectively, this feels like lethargy, brain fog, low motivation, and mental dullness. Redox biology is central to this experience and is often completely ignored. Mitochondria do not just need substrates like glucose or fatty acids; they need a stable redox environment to move electrons efficiently through the electron transport chain. If oxidative stress is high and reducing capacity is low, electron flow becomes inefficient and ATP production suffers. AMPK activation in this redox-unstable environment further reduces energy demand as a protective mechanism. The brain, which has the highest energy demand per gram of tissue, is usually the first place people notice the consequences. Brain fog is a redox and energy throughput problem, not a toxicity signal.

Whose used this? I have some, running 200mg a day, deffo sweat a bit more during cardio, if I combine it with SLU I get a noticeable increase in body temp. Not sure on dosing as see people saying once per day, multiple times etc. Anyone got experiences and share what they have found?