vitamin D3 dosing cuts heart attack risk in half

Standard vitamin D supplementation hasn't shown much benefit for heart health in previous studies, but new research from Intermountain Health demonstrates why: we've been approaching it wrong. In the TARGET-D trial of 630 heart attack survivors, researchers used a personalized approach, monitoring blood levels and adjusting doses to reach optimal vitamin D levels above 40 ng/mL. This strategy cut the risk of a second heart attack by 50%.

More than half of those receiving targeted therapy required initial doses of 5,000 IU daily, far higher than typical recommendations of 600 to 800 IU, and their levels were checked every three months until reaching target. Importantly, no adverse outcomes were observed even with higher doses.

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