Update on my Dad - input welcome!

Hey guys just wanted to give a little update on my Dad's lung cancer journey and see if anyone had any thoughts on his progress. Ideas and inputs greatly appreciated!

Diagnosed with stage 3c lung adenocarcinoma July 2025
Started keto diet, ivermectin 1mg/kg daily and fenbendazole 400mg a few weeks later
Felt strong, good appetite able to walk 2-3km per day, weight 75kg
August 2025 - seen by oncology team in Melbourne and offered 'palliative' chemo and immunotherapy, not eligible for radiation or surgery due to mets to mediastinum and supraclavicular lymph nodes
Had one dose of carboplatin and keytruda September 2025
10 days later admitted to hospital with severe liver dysfunction (enzymes around 1000), presumed autoimmune hepatitis due to keytruda (liver pre treatment was fine)
Commenced high dose steroids and mycophenolate with gradual recovery of liver
Ceased fenbendazole as every time we reintroduced it the liver function worsened. No further immunotherapy of chemo
Continued keto diet (gki 2-5 mostly), ivermectin and gradually added in some other supplements - metformin, berberine, melatonin, quercetin, Artemissinin, ECGC, mebendazole (now 100mg daily), TUDCA, silymarin, vit d with k, Resveratrol
Gradual weight loss since September 2025, down to 60kg
January 2026 finally got off the steroids
January 2026 developed diarrhoea - diagnosed with microscopic colitis presumed due to keytruda from september, ?previously suppressed due to steroids. Required hospital admission for high dose steroids and fluids
No improvement in diarrhoea until infusion of infliximab, now settled and weaning steroids again
Feb 2026 also started IV vitamin C 2ish times per week, can only do 30mg due to problems with the salt load
Ongoing weight loss 56kg, very fatigued and weak, struggling with appetite, out of keeping with improvement in colitis

The good news in all of this is that the cancer has been relatively stable on every scan since metabolic therapy and chemo/immuno. Much to the surprise of his oncologist considering he only had one dose of chemo and immuno.

No new sites of disease, mild interval growth for some of the lymph nodes, small shrinkage on some.

TLDR

Our main problem is the fatigue, weakness and loss of appetite with weight loss. He's had all of the usual screening for causes of this - thyroid, b12, folate, iron, vit d levels etc and the doctors are just saying it is 'multifactorial' ie cancer and lingering colitis. Considering the cancer hasn't moved and prior to SOC treatments he felt good, I'm just wondering if anyone had any ideas on contributing factors and tips for helping him.

The doctors want him to take olanzapine 2.5mg BD as an appetite stimulant, they say at low doses it shouldn't effect mood. I'm very reluctant for him to take an antipsychotic as an appetite stimulant but the low weight is also very worrying.

Thanks guys

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