Hi everyone, I’m just sharing questions I have for my oncologist as he’s a colorectal cancer researcher. I’ll report back on Jan 6 after my appointment with him. I’m not asking questions to the group - I just can’t be fucked changing it to statements because it’s 35 degrees today, feels like 40 degrees and I’m dying 🤣. Hopefully if you have the same risk factors, this could help guide further research. Also, a 10 year HBOT study shows if you do it before and after radiation, side effects were reduced or non-existent in 80% of participants (rectal cancer). It’s only subsided for brain cancer patients in Australia and the TGA are cunts here. But if you can get a subsidy, go for it! It also reduces drug resistance and can improve chemo efficacy. Questions: Have you had any patients on Rapamycin? I have been looking into this and believe there are early stage clinical trials going on for its use in drug resistant colorectal cancer and specifically its synergistic effects with 5-FU, e.g. inhibits mTOR, increases senescence, decreases thymidylate syntheses and angiogenesis etc. Have you ever used or researched inhibitors of ABCG2 pumps to reverse MDR1 over-expression? I noticed the cells in the length of my tumour decreased (assuming these are the neoplasmic cells sensitive to capecitabine) but the width snd height have grown quickly, so perhaps these are the more resistant populations. What is the best way to target VEGF and ANG overexpressions? These are the highest risk factors for angiogenesis that came up on my Onconomics testing, along with FGF, PDGF, and ANG1 and 2. Vabysmo looks promising but can impact eye health. Have you ever used Avastin as an adjunct outside of its use along side other immunotherapy drugs to block VEGF? I have 35% sensitivity to this and there’s promising data when used with chemo or metabolic therapy and HBOT, but Keytruda, Opdivo and Yervoy were completely useless for me because I have normal expression of MMR genes and no MMR deficiency.

Hi warriors! 👋 I have disease progression for the first time since initial diagnosis in June 2023. During the past 5 months I stopped HBOT and drugs from the ReDO protocol. I feel strongly vindicated by this result (albeit a setback) and affirmed that my research, inferences, learnings and previous strategies had me on the right track. This is because I now have strong evidence that the repurposed drugs I selected (based on drug sensitivity testing and oncogene analysis) in conjunction with a fatty meat-based ketogenic diet, HBOT, nutraceuticals etc. works. I think people also need to be warned that there’s lots of “natural healing” crap on social media that isn’t genuine in the context of cancer care - the natural elements are often overstated and used as clickbait and the influencers hide the fact they actually also used SOC (chemo, radiation, immunotherapy and/or surgery) to resolve cancer. It’s only after reaching NED status that they start promoting adjuncts as if they are a stand-alone solution and this is dangerous and deceptive. Yes, I declined SOC and still don’t want radiation, colostomy surgery or intravenous chemotherapy. But everything I have done is backed by scientific literature - I’m not blessing celery juice under a full moon and singing kumbyaya! Clearly, my attempt at “healing” did not work! Stopping the strategies in my previous protocol and eliminating pharmaceuticals did NOT heal my gut. Eating more vegetables for polyphenols and eating less animal protein did not work for me (and I don’t care about all the pro-fibre propaganda - it’s nonsensical to promote eating copious amounts of indigestible plant matter when you have an inflamed colon, compromised permeability, dysbiosis and an ulcerative bleeding tumour!). Just like that after over two and a half years of stability (no growth) and/or results of gradual tumour size reduction, getting closer and closer to NED status … and BOOM: the tumour doubled in size when I followed more “mainstream” medical advice! 💥 The recent PET scan indicates there is 4cm of high avidity in the tumour microenvironment (confirmed by MRI measurements of 20x17x36) so shrimpy boy (my name for the tumour as it literally looks like a mangled bleeding prawn) is certainly still gobbling up glucose! 🤣🍤

Is there anything in blocking Lactate and succinct anti-porters? MCT1, MCT2 and OAT lower he acidic Tumour microenvironment? Yes ketone uptake will also be lowered but MCT4 is still there. We spend our time trying to find inhibitiors of glucose and glutamine but what if we could jam up the cell with lactate and succinate? Would that send the cell towards apoptosis due to the ph drop?

Unfortunately last year I was not able to persuade my wife to try any metabolic approaches, or talk to anyone who advocates them. People will die before changing their habits. She insisted on going the conventional route with the oncologists at Fred Hutch here in Seattle. Her cancer kept progressing slowly, on top of the side effects from the "standard of care" treatment. Her suffering has grown worse and she may succumb or choose "Death With Dignity" within the next few months. We have two daughters, 14 and 16, who are very attached to her. The three of them are like peas in a pod. I have some practical questions, such as whether to keep living in the same place, whether to keep all her stuff (she's a packrat), whether to travel and meet other relatives they haven't seen for a long time. I'd like to hear just from people who've been through something like this.

His YouTube title: Ketosis (Fasting/Ketogenic Diet) accelerates Cancer Growth - New Study. If not, he must be living under a rock if he doesn't know about Prof Seyfried, Dr. Dominic D'Agostino, and many reputable researchers who understand the science behind the ketogenic diet. In a time when C patients are fighting for their lives and searching for hope in ketogenic diet and other metabolic therapies, does this YouTuber muddy the waters even more? 😔 Patients deserve clarity, not confusion. BUT... the good thing is that in the comment section, some folks in the know have pushed back on his narrative. As a follower of Prof Seyfried’s metabolic principle, I gave this YouTuber a thumbs down. What is your take? https://www.youtube.com/watch?v=joa0zk8sb1E&t=161s