So for the past 15 months I’ve been studying alternatives for a lifelong friend with Stage 4 colon cancer. Last week we confirmed our 12 yr malti-poo has bone cancer on his skull above his eye. Well all this prior study on FenBen and metabolic therapy has already been in use for dogs as pet owners adapted the Joe Tippens protocol, and added nutritional supplements for immune support (eg turkey tail mushrooms, etc), and metabolic strategies. So off I go on a journey to transition Boone to ketogenic diet, and FenBen (atleast in the short term). My goal right now is to get him stable with the pain from the tumor and confirm if/how much metastasis has occurred (ie lungs, lymph nodes most likely). Then we decide next steps. Chemo is not favored because track record for remission is poor, and I don’t want to put him through that. A vaccine based immunotherapy clinical trial exists that’s of strong interest but we have to get any metastatic spread under control to be eligible. ———— So that’s the backstory of this past week. This morning I’m reading a research paper about Ketone supplementation. I didn’t even know such product commercially existed. I understand so many of you trying metabolic therapy struggle to get GKI into the target range. I haven’t fully comprehended the conclusions, but it does seem the researchers found benefit for ketone supplementation in the in-vivo mice study. This paper was co-authored by Thomas Seyfried in 2014. Does anyone know if he later determined the results of ketone supplementation was not effective? https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.28809

This case will likely be posted on his X account soon, but I’ll share his summary from my email. The interesting thing I noticed in earlier case studies was the combination of FenBen and Mebendazole. At first I thought both were listed because the person had switched them due to availability. However in this case Dr. Makis adjusted the protocol to take both together. Unfortunately, he doesn’t explain the rationale. That’s 3000 Mg/day combined. I thought that the two drugs were very close cousins and with same proposed mechanisms of action. ——— 59 year old Pennsylvania woman (non-smoker, no 2nd hand smoke, never smoked pot, no drugs) with Stage 4 Lung Ca metastatic to nodes, bones, brain In May 2025 she started: - Ivermectin 1.5mg/kg/day - Fenbendazole 1000mg/day In October 2025 she started: - Ivermectin 1.5mg/kg/day - Fenbendazole 1500mg/day - Mebendazole 1500mg/day KEY POINTS: This case is special because it shows the success of something I developed over a year ago - combining three anti-parasitics: Ivermectin, Fenbendazole, Mebendazole. This is something that no one else is doing.

This is a very interesting read about Glutamine and the tradeoff of its role for cancer cells vs. need for our immune system. Its from a Substack I’m subscribed but here is a web link. Hopefully, it’s accessible. If not, it is available to subscribe for the free portion of his Substack. You may also find it interesting to read up about this person’s launch as a source for ordering IVM, Fenben, Meben. I find this Substack very helpful with educational info. https://brighterworkscanceralternatives.substack.com/p/glutamine-and-cancer-metabolism?r=57wc2h&utm_medium=ios&triedRedirect=true

The results of the 3 case studies are similar to email updates Mr Makis publishes for cancer patients he consults. The interesting info here is the length of time the patients continue taking FenBen after reaching remission. That’s often a question his clients ask in their emails after having achieved good results with the protocol. As far as I can recall he’s never answered that question in his recap summary. https://pmc.ncbi.nlm.nih.gov/articles/PMC12215191/

Today is all saints day, and here is a link to the patron saint of cancer. https://catholicsaintmedals.com/saints/st-peregrine/