Collagen: The “Glue” Holding You Together (And Why You’re Probably Not Thinking Big Enough About It)
When most people hear collagen, they think “wrinkles” and maybe “creaky knees.”
But collagen is far more than a beauty supplement or a joint helper. It’s literally the scaffolding that holds your entire body together – from your gut lining to your blood vessels to your bones and fascia.
Let’s zoom out and look at collagen the way your biology “sees” it.
What exactly is collagen?
- Collagen is the most abundant protein in the body, making up about 30% of your total protein.
- It’s the main structural protein in skin, bones, tendons, ligaments, cartilage, fascia, blood vessels, and the intestinal lining.
- Think of it as a tough, rope-like triple helix that gives tissues strength and shape, while elastin gives them stretch.
There are at least 28–29 types of collagen, but most of your body is built from a core few:
- Type I – skin, bones, tendons, ligaments, teeth
- Type II – cartilage and joints
- Type III – blood vessels, hollow organs, skin (with type I)
- Type V & X – support bone, joint surfaces, and specialized tissues
When collagen is abundant and well-organized, tissues are strong, springy, and resilient. When it’s damaged or depleted, you feel it – not just on your face, but everywhere.
Why collagen declines (and why midlife women feel it hardest)
Starting in our mid-20s, collagen production naturally drifts downward. Sun damage, smoking, high sugar intake, chronic inflammation, and poor sleep all accelerate the breakdown of collagen fibers.
For women, the big cliff is menopause. Estrogen normally stimulates fibroblasts (your collagen-making cells). As estrogen drops:
- Up to ~30% of skin collagen can be lost in the first five years after menopause, followed by ~2% per year after that.
- Skin gets thinner, drier, and less elastic. Joints, fascia, and pelvic tissues also feel the loss.
On top of that, fibroblasts can shift from making more elastic type III collagen toward stiffer type I collagen, the kind found in ligaments and scar tissue. That’s one reason midlife can feel like a season of “tight, brittle, and creaky” instead of “bouncy and flexible.”
Collagen’s jobs all over the body
1. Skin, hair, and nails
This is the role everyone knows – but let’s ground it in data:
- Multiple randomized controlled trials show that oral collagen peptides (around 2.5–10 g/day) can improve skin hydration, elasticity, and wrinkle depth compared to placebo.
Collagen doesn’t work like Botox; it’s more like sending the right building blocks and signals to your dermis so it can thicken and repair from the inside out.
2. Joints, tendons, ligaments & recovery
Types I, II, and X collagen dominate your cartilage, tendons, and ligaments.
Research suggests that:
- Collagen supplementation can support joint comfort and function, especially in osteoarthritis or high-impact athletes.
- It may help maintain tendon and ligament integrity, which matters for anyone lifting weights, running, or simply wanting to avoid “mystery tweaks” in midlife.
Because collagen is rich in glycine, proline, and hydroxyproline, it also feeds your muscle and connective-tissue repair after training.
3. Bone strength & fracture resistance
Bones are not just calcium sticks – they’re a collagen matrix that minerals crystallize onto. Roughly 70–80% of bone organic protein is collagen.
Several studies in postmenopausal women show that collagen peptides:
- Can increase bone mineral density and improve markers of bone formation over 1–4 years.
This is huge when estrogen is dropping and bone loss is accelerating.
4. Gut lining & microbiome support
Your intestines are lined with a collagen-rich extracellular matrix and tight junctions that keep the barrier intact.
Emerging research shows that collagen peptides can:
- Enhance tight-junction proteins and improve barrier function in cell and animal models.
That doesn’t mean collagen “cures leaky gut,” but it does suggest that a collagen-rich environment helps your gut lining stay sealed, soothed, and better able to recover from stress.
5. Cardiovascular system & blood vessels
Collagen is woven throughout your blood vessel walls, heart valves, and the connective tissue around the heart.
- Imbalances in collagen types and cross-linking are part of arterial stiffness and fibrosis, both key players in cardiovascular disease.
- A recent meta-analysis suggests that collagen peptide supplementation may modestly improve certain cardiovascular risk markers, like arterial stiffness and lipid profiles.
Again, collagen isn’t a replacement for medical care, but it’s an important part of the structural health of your arteries.
6. Fascia, connective tissue & overall mobility
Collagen forms the web of fascia that wraps around muscles and organs. Healthy fascia:
- Allows smooth gliding of muscles
- Helps distribute force through the body
- Plays a role in posture and pain
When collagen becomes brittle or disorganized (think advanced glycation end products from excess sugar, or years of micro-trauma), tissues can feel stiff, restricted, and more injury-prone.
Supporting collagen plus regular movement, stretching, and strength training is key for staying mobile as you age.
7. Nervous system, sleep & detox support (hello, glycine)
Collagen is naturally rich in glycine, an amino acid that:
- Acts as a calming neurotransmitter
- Helps form glutathione (your master antioxidant)
- Supports liver detox pathways
Several small studies suggest glycine before bed may improve subjective sleep quality and next-day fatigue – one reason many people feel “sleepier and calmer” when they take collagen in the evening.
How to support your body’s collagen
Your body can make collagen, but only if it has the raw materials and the right environment.
Key building blocks & cofactors
- Vitamin C – absolutely essential for collagen cross-linking.
- Amino acids – especially glycine, proline, hydroxyproline (found in collagen-rich foods and supplements) and overall protein intake.
- Minerals – zinc, copper, manganese, iron all play roles in collagen synthesis and antioxidant defense.
Lifestyle habits that protect collagen
- Prioritize quality sleep and stress management (high cortisol breaks down collagen).
- Avoid smoking and excess alcohol.
- Limit ultra-processed sugar and high-heat fried foods, which increase glycation and stiff, brittle collagen.
- Use daily sun protection for skin.
- Lift weights and move your body – mechanical loading sends “build more collagen” signals to bone, tendon, and fascia.
Supplements are not magic, but they can be a powerful adjunct when the basics are in place.
Why a multi-type collagen matters
Because different tissues rely on different collagen types, it often makes sense to use a multi-collagen formula rather than just one isolated type.
For example:
- Type I – skin, hair, nails, bone, tendons
- Type II – cartilage and joint surfaces
- Type III – blood vessels and organs, works alongside type I
- Type V & X – bone matrix, joint surfaces, and specialized connective tissues
A well-designed multi-collagen can support skin + joints + bone + gut + vasculature at the same time.
Where Our “Collagen+” fits in
Your Collagen+ formula is built with that “whole-body collagen” mindset:
- Five collagen types (I, II, III, V, X) from bovine, fish, chicken, and eggshell membrane – designed to support skin, hair, nails, bones, cartilage, and connective tissue throughout the body.
- ACTIValoe® (active aloe) to help support gut mucosal health and improve absorption of nutrients.
- Fulvic acid to assist mineral transport and cellular uptake.
- Helps trigger the body’s own production of hyaluronic acid, which supports joint lubrication and skin hydration (a nice synergistic partner for collagen).
Used consistently, a product like Collagen+ isn’t just about “plump skin” – it’s about feeding the entire collagen network: fascia, vessels, joints, bones, and gut lining.
Important note: Collagen supplements are not intended to diagnose, treat, cure, or prevent disease. They’re a nutritional tool – one piece of a bigger lifestyle strategy that includes whole-food nutrition, movement, sleep, and appropriate medical care when needed.
Collagen is not a vanity protein. It’s:
- The rebar in your bones
- The scaffolding of your skin
- The padding in your joints
- The mesh of your gut barrier
- The framework of your arteries and organs
As we age – especially through perimenopause and menopause – that collagen network thins and stiffens. Pairing smart lifestyle habits with a well-formulated multi-collagen (like Collagen+) can help you nourish that infrastructure so you move, look, and feel more like yourself for longer.