Sleep issues are often driven by circadian disruption, stress, and nervous system imbalance, not just lack of sleep pressure. In peptide research, several compounds have been studied for supporting sleep quality and regulation, rather than acting as sedatives. Key peptides discussed in sleep research: - DSIP (Delta Sleep-Inducing Peptide): Studied for its potential role in deep sleep and sleep initiation, especially in stress-related sleep disruption. - Epithalon (Epitalon): Researched for circadian rhythm and melatonin signaling, often used in short cycles to support sleep–wake timing, particularly with aging. - Selank: Commonly discussed for anxiety reduction and calming the nervous system, helpful when sleep issues are driven by a racing mind rather than difficulty staying asleep. - Semax (Indirect): Studied for cognition and stress resilience; may indirectly improve sleep by supporting daytime cortisol and neurological balance. - GHK-Cu (Indirect): Not a sleep peptide, but its role in recovery, inflammation control, and nervous system health may support better sleep quality over time. Sleep-related peptides aim to normalize physiology, not sedate. Benefits are typically gradual and work best alongside consistent light exposure, stress management, and regular sleep timing. Educational discussion only — not medical advice.