3h • General Discussion
Unlock Brain Health: How The Vagus Nerve Shields Against Neurodegeneration
The vagus nerve critically modulates neurodegenerative diseases (NDs).
It operates via the gut-brain axis.
Vagus efferents transmit gut-derived signals, mainly short-chain fatty acids (SCFAs), to brainstem nuclei.
These signals inhibit HDAC6 in neurons.
This inhibition promotes tubulin acetylation and microtubule stabilization.
Conversely, vagotomy induces microtubule depolymerization and impairs axonal transport.
Vagus stimulation restores microtubule networks.
It also reduces protein aggregates by 45% and improves behavioral outcomes.
The vagus nerve acts as a gut-to-brain conduit.
It fortifies neuronal microtubules, potentially paving the way for non-invasive stimulation therapies.
More info:
Ever feel like your gut's calling the shots? Turns out, it might be!
New research highlights the mighty vagus nerve. It's not just for digestion.
It's a superhighway from your gut to your brain. Think fiber-fueled texts from your microbiome.
These texts? Short-chain fatty acids (SCFAs). They tell your brain cells to tidy up!
SCFAs help stabilize microtubules, the cell's support beams. Like rebar in concrete.
Without this gut-brain chat, those beams get wobbly. Hello, neurodegeneration!
Scientists used fancy tools: lasers, microscopes, even rodent obstacle courses.
The verdict? A happy vagus nerve equals happy brain cells. Less gunk, more function.
Vagus nerve stimulation? The future of brain health? Maybe!
So, listen to your gut! Your brain might thank you for that next salad.
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Unlock Brain Health: How The Vagus Nerve Shields Against Neurodegeneration
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This group is designed for the discussion of the Vagus Nerve, techniques to stimulate it, and the benefits of doing so.
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