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Chinese Chemicals - Group Buy!
Q: What are Chinese Chemicals? A: These are very popular products to help research based education for biohacking. Q: What is a group buy? A: A group of researchers pool resources to buy Chinese chemicals in bulk. Then split the cost of testing the products (optional) Q: Are group buys safe? A: Yes, if you find a reputable buyer you can trust. They place a bulk order and then redistributes the order among the group purchase. 🚨 We are taking group orders, deadline is January 23, 2026. 🚨
GLP: NOT “WHICH IS BEST.” WHICH IS RIGHT.
❇️ Everyone wants to know: Is Reta better? But “Better” depends on what you’re measuring and what matters to you. Here’s an honest comparison of al three GLPs Sem - GLP-1 Triz - GLP-1 + GIP Reta - GLP -1, GIP and Glucagon Weight Loss: The Numbers Average weight loss in major trials: Medication - Duration - Weight Loss Sema 2.4mg - 68 weeks - 14.9% Tirz - 75 weeks - 20.8% Reta - 68 weeks - 28.7% 👉🏼 Important: These are different trials, different populations. Not head-to-head. Tolerability: Who Stops Discontinuation rates due to side effects: Medication - Drop Out Rate Sema 5-7% Tirz 7-10% Reta 12-18% 👉🏼 Higher efficacy seems to come with higher dropout rates. This is a real trade-off to consider. ⚠️ Side Effects Profiles All three share: - Nausea, vomiting, diarrhea, constipation  - Decreased appetite  - Generally dose related 👉🏼 Reta has additional side effects: - Dyesthesia (abnormal skin sensations): up to 21% - Potentially more intense GI effects at high doses  ❇️ What’s NOT Being Compared: Critical Gaps: - No head to head trial exists between GLPs - Long-term data for Reta limited to 68 weeks - Cardiovascular outcomes not yet available for Reta - Real world effectiveness may differ from trial results  These are controlled trial comparisons - not guarantees. Different Medications, Different Situations 1️⃣ Sema may be right if: - You want the most long-term safety data  - Lower intensity side effects preferred  - Cost/access is primary concern  2️⃣ Tirz may be right if: - You want more efficacy than Sema  - Good balance of results and tolerability  3️⃣ mReta might be right if: - Maximum efficacy is a priority  - Willing to accept potentially more side effects The right GLP choice depends on YOUR goals, timeline, and how your body responds.More options is good for everyone!
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LITTLE KNOWN PEPTIDES: ABALOPARATIDE
Abaloparatide - the bones peptide! 🦴 ❇️ What it does - Binds to PTH1 receptors on bone-forming cells (osteoblasts) - Stimulates new bone formation - Improves bone density and bone strength - Does this with less stimulation of bone breakdown compared to similar peptides ❇️ Abaloparatide Peptide Abaloparatide is a synthetic peptide modeled after a portion of the body’s parathyroid hormone–related protein (PTHrP). It has gained attention in scientific research for its role in bone formation and skeletal signaling pathways. Unlike compounds that focus only on slowing bone loss, abaloparatide is studied for its ability to stimulate new bone development, making it an important compound in bone metabolism research. ❇️Abaloparatide works by interacting with PTH1 receptors located on bone-forming cells known as osteoblasts. This interaction activates signaling pathways that promote new bone formation, increase bone density, and improve overall bone strength and structure. Its receptor selectivity favors anabolic, or bone-building, activity while minimizing signaling associated with bone breakdown. This targeted mechanism is what differentiates abaloparatide from other bone-related peptides under study. 📚 Research has shown abaloparatide to be relevant in studies focused on bone density, skeletal remodeling, fracture-risk reduction models, and bone microarchitecture. Because of these properties, abaloparatide has been widely explored in laboratory and clinical research environments related to osteoporosis and bone health science. 🦴Abaloparatide is a bone-focused research peptide that supports signaling pathways involved in building stronger, denser bone. Its emphasis on bone formation and structural integrity makes it a valuable compound in ongoing skeletal research. 🧬 Research-Only Use:This compound is sold strictly for in vitro laboratory research purposes only. It is not intended for human or veterinary use, nor for diagnostic or therapeutic purposes. No claims are made regarding safety or efficacy in any clinical application.
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PCOS and GLPs
This isn’t just “lose weight” → ovaries work better.” GLP -1s show benefits beyond weight loss for those with PCOS. They also improved reproductive functionality. 🔍 ⚠️ the 2023 international evidence-based PCOS guidelines now recommend GLP-1s for PCOS in research settings. Research is promising, but we need more long-term data and this decision shouldn’t be taken lightly - as they come with side effects. ⚠️ How do they work? It’s not just from a knock on effect from the metabolic effects which we already know about, it’s literally signaling your ovarian cells to function more normally. ‼️86% ovulated on GLP-1 + metformin (vs 29% metformin alone) 🔄 62% had more regular periods. 🤰🏻 IVF pregnancy per transfer: 86% (typical PCOS rate 30%) 📉 Testosterone dropped How GLP-s work for PCOS at multiple levels: 🧠 Brain: modulates hypothalamic pathways to optimize hormone release 🥚 Ovaries: GLP-1 receptors exist IN your ovaries. It works directly on folic development, reduces cystic follicles, supports normal ovulation 📌 Insulin: improves insulin sensitivity. This is crucial because high insulin drives your ovaries to overproduce testosterone - fix the insulin, help reduce the androgens. 🔥 Inflammation: GLP-1s reduce inflammation markers which improves both metabolic health AND helps your ovaries function normally.
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Dosing and reconstitution
Hello, I am currently taking a compounded Tirzepitide. I believe it is a 2ml bottle that contains 6 mg of Tirzepitide. I draw up .42 units each time which is a very low dose. How do I do the same dose with a 20 mg bottle of Tirzepitide?
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