OpenAI, in collaboration with Retro Bio, has developed a custom AI model (specifically "GPT-4b micro") that can design engineered variants of the Yamanaka factors, which are proteins used in cellular reprogramming. The Role of OpenAI and Yamanaka Factors Yamanaka Factors: These are a set of four specific proteins (OCT4, SOX2, KLF4, and c-MYC) discovered by Shinya Yamanaka in 2006. They are capable of turning mature, specialized body cells (like skin cells) back into induced pluripotent stem cells (iPSCs), which can then develop into almost any cell type. OpenAI's Contribution: Researchers at OpenAI and Retro Bio trained an AI model on protein sequences, biological text, and 3D protein structures. This model was used to design novel variants of the original Yamanaka factors. Result: The AI-designed factors achieved a 50x increase in reprogramming efficiency in laboratory settings compared to the standard proteins. This breakthrough could significantly advance regenerative medicine and drug discovery by making the process of creating stem cells faster and more efficient.

Excellent short and simple biosensor explainer for farming, medical and environmental science. https://youtu.be/we1O56mJ6lE?is=VD35w4-GT-PKFJHf

Dr. Jack Kruse links ancient Mayan (and broader Mesoamerican) structures—primarily pyramids and volcanic basalt architecture—to a form of "original Neuralink" technology for handling geomagnetic excursions and maintaining biological coherence. threadreaderapp.com This idea appears in his recent X thread (and teased blog) connecting quantum biology, light/water/magnetism (LWM), deuterium management, and Earth's weakening magnetic field (e.g., South Atlantic Anomaly/SAA effects). It is speculative/fringe but grounded in his broader theories on piezo/pyroelectric collagen, semiconduction in tissues, proton spin, and 160 THz (UV/IR-related) signaling in biology. threadreaderapp.com Core Concept: Pyramids and Basalt as Magnetic "Devices"Kruse describes Mayan pyramids (e.g., in Yucatán, Guatemala, near cenotes) not primarily as tombs or calendars, but as passive magnetic transducers, "lighthouses," or "isotopic rectifiers" built during periods of magnetic instability: threadreaderapp.com Magnetic flux concentration: Pyramids (often stepped, high-aspect-ratio) act like reverse volcanoes or funnels. They couple Earth's crustal magnetic field (Z-axis/inclination) to the ionosphere and a hypothesized "Universal Stator" (cosmic magnetic fields). This is said to "pin" proton spins and prevent dielectric collapse in water/tissues. threadreaderapp.com Basalt/paramagnetism: Mayans favored volcanic basalt stone (rich in magnetite/iron, highly paramagnetic). It acts as a "solid-state magnetic amplifier" or antenna, gathering/amplifying flux lines. Black sand beaches in places like El Salvador (volcanic) are seen as decentralized paramagnetic arrays. Volcanic rock reportedly retains "magnetic memory" from past field strengths. threadreaderapp.com Water interaction (cenotes/aquifers): Built over water sources (magnetic dipoles). The structure allegedly creates vortex effects (à la Schauberger) for isotopic fractionation—separating deuterium (D+) from protium to produce deuterium-depleted water (DDW). This supports structured/"living" water, better semiconduction in collagen/stroma, and resists "viscosity shifts" linked to disease (e.g., lymphedema, cartilage issues in his follow-up post).

Interesting what can be done remotely to the cells. https://www.cell.com/cell/abstract/S0092-8674(26)00330-2

https://open.substack.com/pub/biogenesishealing/p/the-frequent-flyer-heart-problem?utm_source=share&utm_medium=android&r=z7cdu