Ok ya'll this has been life-changing for me!
For 30 years, I have been trying to live the healthiest lifestyle I possibly could with the information that was available to me and within my resources.
No matter what I did, there always seems to be something else.
(I'm gonna cut to the chase and skip all of the things I have done to try and stay and then get healthy.)
About a year ago, I heard about this gene mutation that makes it difficult to absorb vitamin B or something like that. Then after the new year a few of my family members were talking about it and turns out some of them have a MTHFR Variation (along with other ones.) When I read more about this and adjusted my supplements, it seems like all the work I've been doing is finally coming together! I can tell that all of the supplements and nutrition I have been giving to myself is finally working! My body is no longer fighting against itself to detox, I'm actually detoxing. It's not even 2 months since I made the adjustment, but WOW can I see the difference.
It has really been that big of an improvement in my stamina, relieving chronic pain and inflammation, and I'm assuming some gut repair and other things are going on.
They say that, "40-60% of the population has this gene mutation, which interferes with normal DNA production and repair, immune function and detoxification." MTHFR is necessary for methylation and in converting folic acid to methylated folate.
"MTHFR refers to the methylenetetrahydrofolate reductase gene, which provides instructions for an enzyme that plays a role in processing folate and other B vitamins. A common genetic variation in the MTHFR gene, known as a variant, can affect how this enzyme functions, potentially leading to elevated levels of homocysteine in the blood and other health consequences. " Some research suggests links between MTHFR variants and conditions like heart disease, stroke, and depression.
Increase Folate (NOT folic acid) Intake: Focus on natural sources of folate, such as leafy greens (spinach, kale), legumes (beans, lentils), nuts, and fruits (avocado, citrus fruits).
Limit Processed Foods: These often contain folic acid, a synthetic form of folate, which may not be effectively utilized by people with MTHFR mutations.
Limit anything that is Enriched or Fortified. - Now I know why I never liked Nutritional Yeast. 🤮
Increase Protein Intake: Higher protein intake supports methylation, a critical biochemical process that can be inefficient in those with MTHFR mutations.
L-Methyltetrahydrofolate & methylcobalamin: This is the bioactive form of folate, more effective for those with MTHFR mutations than synthetic folic acid. Folinic acid and hydroxycobalamin are alternatives for those who are sensitive to methylated B’s.
Omega-3 Fatty Acids: To support heart health, especially important given the increased risk of cardiovascular issues associated with MTHFR mutations.
Make sure B vitamins are methylated.