This is my answer: My responsibility is to protect both the patient and the company. I always lead with respect for the physician’s clinical judgment, and I acknowledge that they have a deeper understanding of their patient’s specific case. That said, if the proposed use is off-label, I make it clear that I cannot support or be present for the procedure in the OR/Lab. I explain the potential implications for patient safety, liability, and future outcomes. I also offer to connect them with other physicians who may have faced similar situations, so they can have a peer-to-peer discussion. My goal is to stay collaborative and supportive—while always staying compliant.