🔬 SLU-PP-332: The "Exercise Mimetic" - But Lifestyle First
Deep Dive SLU-PP-332 - the compound everyone's calling an "exercise in a pill." The science is legit, but let me be clear upfront: This is NOT a replacement for actual training and lifestyle habits. What Is It? SLU-PP-332 is a synthetic compound that activates estrogen-related receptors (ERRs), particularly ERRα, which regulates mitochondrial biogenesis and energy metabolism. Despite the name, it has nothing to do with estrogen. How it works: It activates the same metabolic pathways triggered by endurance exercise - turning on genes for energy expenditure, fat metabolism, and cellular repair. The Research Results In obese mice treated for 28 days: gained 10x less fat, lost 12% body weight, increased fatty acid oxidation by 25% - all while eating the same and not exercising more . In normal-weight mice: ran 70% longer and 45% further than untreated mice. Additional benefits seen in studies: improved cardiac function, reduced inflammation in aging kidneys, and neuroprotective effects. Research Dosing (Research/Anecdotal) ⚠️ Important: SLU-PP-332 has not undergone human clinical trials. That said, here's what is being experimenting with: Lower Range: 250mcg - 1mg daily - Typical starting point - Subtle metabolic effects - Testing tolerance Moderate Range: 5-10mg daily - More noticeable effects reported - Common maintenance dose Mega Dosing: 20mg - 400mg daily - Extreme high end - All administered as oral capsules - Used by aggressive self-experimenters - Unknown safety profile at these doses Note: Research in mice used 50mg/kg twice daily (significantly higher relative dose than most humans are using). My Standpoint: Master The Basics FIRST Before even considering SLU-PP-332, you need these dialed in: ✅ Training: 4-6 days/week consistently (resistance + cardio) ✅ Nutrition: Whole foods, adequate protein, proper calories ✅ Sleep: 7-9 hours nightly ✅ Stress Management: Not chronically fried ✅ Consistency: 80%+ adherence for 6-12 months minimum