Hi everyone, I noticed some people have commented that they’re struggling to get their GKI below 2 and/or maintain it. So I thought I’d share some tips. I am day 6 into a 14 day fast. This time I am experimenting with a tea fast of matcha, dandelion root and graviola leaves - they all have very promising data indicating evoking of apoptosis in colorectal cancer cells (and other cancer cells too). They may prevent cancer cells using autolytic cell cannibalism to their advantage (whereby they eat surrounding cells in fermentation-driven stress situations) and give this advantage to T-Cells and NK cells to eat the cancer cells instead. Also, they may reduce glutamine’s capacity to be transported and converted to glutamate. Anyway, I have been able to maintain a GKI of 0.3-0.7 when I am in my “pulse” phase with the following strategies: 1. Fasting for 48 hours - sometimes dry, sometimes water-only and sometimes fat-only - they all have produced similar results, but dry fasting is king! 2. Don’t measure ketones and blood glucose within 2 hours of exercising or waking up and be disheartened - your glucose will be naturally higher as it’s the first fuel source drawn on for anaerobic activity (but ketones will eventually be used over time) and due to the “dawn effect” 3. Gluconeogenesis from protein can increase your blood glucose levels, as well as muscle cannibalism during fasting, so drop your protein intake and/or lift weights to prevent this (disregard the short blood glucose increase - this will stop once you’re fully depleted of glycogen). But don’t overdo it - aim to maintain rather than grow because hypertrophy will stimulate mTOR signalling and throw off autophagy. 4. Don’t only rely on ketone supplements and huge amounts of fat - teach your body to use its own fat because it is not just ketones but the metabolic process of ketogenesis that is effective in metabolic therapy. Also, if you eat a lot of fat and take a lot of ketone supplements, this may drive down your blood glucose reading but your insulin could still be high (which we can’t measure regularly and hyperinsulinemia is a driver of tumour growth). 5. If safe to do so, consider fasting to evoke deeper ketosis. For example, in the first day of fasting my GKI was 4.1. On the second day it was 3.2. Then on the third day, it drove down to 0.7 and has been 0.5-0.7 on days 4, 5 and 6. If you are worried about undesired weight loss or feel unwell when fasting, fat fasting is more gentle and won’t block autophagy as fat has zero impact on insulin. This includes bullet proof coffee, e.g. a little butter and MCT oil but NOT cream. 6. Monitor your GKI more closely after you break the fast - you should not go above 2 unless you’re eating too much protein or (like me) have a mindless, carb-addict relapse! 7. Get over the uncomfortable feeling that comes with going from being jacked to skinny as fuck. I totally get it because I used to be so muscular and with each fast I end up looking like I’ve just come out of a labour camp by the end. But at the end of the day, the longer you can go (safely of course and under medical monitoring or at least with a supportive friend or family member) the better your GKI outcome will be.

Prostate Cancer Gleason 3+4=7 (Jan 2025) - any success with combination of Keto and IVERMECTIN/Fenbendazole?. I'm doing Keto for last six months + D3+K2, Fish Oil, B12, Berberine and recently added Magnesium and Curcumin. My prostate size decreased from 40 (Jan 2025) to 31 (Oct 2025), and my PSA stopped growing over this time, but per MRI the lesion is increased in size from 1.0 (Dec 2024) to 1.8 (Oct 2025). I dropped 35 lbs. Stopped using Berberine, but my cholesterol is more than 300 now...used to be ~ 100. Any success using IVERMECTIN/Fenbendazole for similar problem? Any advise please