Dec '25 • General discussion
The Phase 3 Reta Trial results are insane!
Reta quietly set a new celling for weight loss compounds, with a whooping up to 29% body weight lost!
Reta is a triple hormone agonist that targets (GIP, GLP-1 and Glucagon), that hit THREE pathways simultaneously for enhanced fat metabolization and metabolic effects.
Protocol:
- once a week use
- start at 2mg, titrated very 4 weeks
- reach target dose of 9-12mg gradually. Do not exceed max recommended dose.
Weight loss
In trial nearly 1 in 4 participants lost over one-third of their body weight. this level of response was previously unheard of in obesity drug trials and suggests Reta may fundamentally reset what's considered possible.
Pain reduction
Trail participants with knee osteoarthritis experienced:
- 76% reduction in knee pain
- significant improvements in physical function
- some participants reported complete pain resolution
Cardiovascular and metabolic markers
beyond body weight Reta improved several key health markers:
- lower non-HDL cholesterol
- reduced triglycerides
- lower hs-CRP (systemic inflammation marker)
- reduction is systolic blood pressure
This shows Reta isn't just shrinking fat mass (also helps support lean muscle), it's improving metabolic and cardiovascular risk profiles which his critical for long-term health outcomes.
SIDE EFFECTS
What you need to know is Reta is not just powerful, it's aggressive.
At higher doses, a new side effect showed up called dyesthesia (an abnormal sensation of touch). At 9mg about 1 in 9 people felt it, at 12mg it jumped to 1 in 5 people. This is all a dose-dependent neurological signaling, making people stop using Reta.
GI side effects were common: nausea, vomiting, diarrhea... nothing shocking here. But what was shocking is that the discontinuing rate was 12-18% in the treatment groups, which is relatively high in comparison to other GLPs. That's the trade off when you push too hard at higher doses, and you shouldn't.
We have Reta 20mg in stock- $55 per vial.
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The Phase 3 Reta Trial results are insane!
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