Podcast Episode 9 | B2B Cold Email 101 2025

Episode Summary:

In this in-depth tactical session of the NextGen Sales Leaders Podcast, host Benjamin Reed breaks down the fundamentals of cold email, covering everything from lead generation, list building, copywriting, AI-driven personalization, inbox management, and deliverability.

If you’re looking to master cold outreach, understand how many emails to send, when to send them, and how to optimize your campaigns for maximum reply rates and conversions, this is the episode for you.

Ben walks through the core components of cold email success—ideal customer profile (ICP) creation, structuring email copy for AI-driven personalization, managing email deliverability, and setting up your cold email infrastructure with Instantly, Clay, and other key tools.

He also provides a detailed breakdown of how many emails you need to send to hit your sales targets, the cost of running a cold email operation, and the realistic ROI you should expect.

What You Will Learn:

How to identify and build hyper-targeted cold email lists
The best structures to use and how to personalize at scale
The right way to configure inboxes, warm-up sequences, and avoid spam filters
Understanding the tools, costs, and sending limits to optimize your outbound system
The best way to convert cold leads into booked meetings
Key benchmarks for reply rates, meeting rates, and customer acquisition costs