Pasteurella, often called “snuffles,” is one of the better-known bacterial diseases in rabbits. It is most commonly associated with Pasteurella multocida and can cause sneezing, thick white or yellow nasal discharge, wet front paws, raspy breathing, pneumonia, ear infections, abscesses, reproductive infections, and in severe cases systemic disease. One of the confusing things about Pasteurella is that exposure does not always mean illness. Some rabbits may carry the organism without obvious symptoms, while others develop clinical disease when stress, environment, bacterial load, concurrent illness, or individual susceptibility tip the balance. For breeders, that means there are really two separate questions: can an individual rabbit be treated, and should that rabbit remain in a breeding herd? Those are not the same question. Culling Is Still the Primary Herd-Control Tool Antibiotics can save individual rabbits, but they do not replace herd selection. In a breeding program, repeatedly treating rabbits that develop respiratory disease can keep animals in the herd that consistently fail to remain clinically healthy under normal conditions. It can also maintain infectious pressure within the rabbitry. That does not mean every rabbit that develops Pasteurella has “bad genetics.” Heat, poor ventilation, ammonia, transport, pregnancy, stress, concurrent infections, and exposure level can all affect disease expression. But long-term herd management should still favor rabbits that stay healthy. For that reason, culling clinically affected breeding rabbits remains our preferred approach. Treatment is reserved for special cases. Where Draxxin Comes In Draxxin is the trade name for tulathromycin, a long-acting macrolide antibiotic. It is not labeled specifically for Pasteurella in rabbits, so its use in rabbits is extra-label. However, published research has shown promising results. A 2017 study by Edrees, Abdellatief, and El-Sharkawy found that tulathromycin significantly improved clinical signs, mortality, growth, blood values, and tissue damage in rabbits experimentally infected with Pasteurella multocida.