What it is
VIP is a naturally occurring neuropeptide involved in communication between the nervous system, immune system, and gut.
What it’s known for
Supports neuro-immune balance
Plays a role in gut motility and absorption
Influences vasodilation (blood flow signaling)
Involved in circadian rhythm and stress signaling
Why people talk about it
VIP sits at the intersection of brain ↔ gut ↔ immune signaling, which is why it shows up in discussions around bio-optimization and recovery-focused research.
Quick notes
Short half-life
Very signaling-specific
Typically discussed in advanced protocols