For a personal mortgage, I think a 50 year mortgage is a terrible idea. Ultimately you'll pay SO MUCH more for your home, so even though it may lower the initial barrier with a lower payment, I don't think it is worth it over the long run. With that being said, I do question whether the equation is different when you are considering a real estate investment property as part of your business. With a plan to exit in <10 years, I'm not sure that the difference between a 30 yr and 50 yr are that different and payments would be lower allowing better cashflow. You'll pay down less of the principal, so you'll have less equity when you sell, but that may be okay, if you had more cash flow while you owned (and you can always pay more than the monthly payment if you want to pay of principal faster). Interested in other people's thoughts...

@Prateek Donni I think it can be different depending on whether you have a W-2 or not. For those of us who have existing W-2s and are high earners (or have a spouse that is a high earner), being able to write off a significant amount of your income and therefore lower your tax burden and maybe even your tax bracket is a significant benefit. For example, if you are earning $700K in your W-2 (35% tax bracket) and with bonus depreciation you can write of $350K, you save all the taxes on that $350K (over $100K). If you or your spouse do not have a W-2 and you are all in on STRs, that is a bit of a different situation. I'll leave that more to the experts. :)