I see a lot of controversy around the correct epithalon dosage. I want to know your guys input on it person use and what the research says. I see that in capsules form it’s around 3-6mg, when it comes to injectables I see anywhere from 1-10mg a day.

I know Derek wrote about this but I couldn’t find the post. I genuinely curious why should we trust in a 1 vial or even 3 vial test? Out of the hundreds to thousands of vials that have

Let's talk about one of the most underrated nootropics in the research space and my personal favorite - Bromantane. Remember all of this content is research use only and not medical advice. What Is It? Bromantane is an adaptogenic stimulant originally developed in Russia in the 1980s for their Olympic athletes. It's classified as an actoprotector - meaning it increases physical performance without increasing oxygen consumption. How Does It Actually Work? This is where Bromantane gets interesting - it doesn't work like typical stimulants. The Enzyme Upregulation: - Tyrosine Hydroxylase (TH) - Bromantane increases the activity of this enzyme, which is the rate-limiting step in dopamine production. More TH = more dopamine being MADE, not just released - Tryptophan Hydroxylase - Same deal but for serotonin production. You're literally increasing your brain's capacity to produce these neurotransmitters Why This Matters: Most stimulants (caffeine, amphetamines, etc.) force your neurons to DUMP their existing dopamine stores. You feel great... then you crash because the tank is empty. Bromantane says "let's make the tank bigger AND fill it faster." You're increasing baseline production capacity. The GABAergic Component: Bromantane also modulates GABA receptors, which is why you get stimulation WITHOUT anxiety. It's calming and energizing at the same time - something most stims can't pull off. Research Observations: - Increases Dopamine & Serotonin - Through enzyme upregulation, not depletion - Reduces Anxiety - GABA modulation keeps subjects calm - Boosts Energy & Motivation - Clean, sustained mental energy - Enhances Focus - Improved cognitive performance and mental clarity - Neuroprotective - Protects brain cells from stress and oxidation - Improves Physical Performance - Increases work capacity without taxing the cardiovascular system as much Typical Research Dosing: - Research dose: 25-50mg per day - Timing: Morning or early afternoon (can affect sleep if taken late) - Cycle: 4-6 weeks on, 2 weeks off

I'm trying to pinpoint some good topics for courses and peptide education that you guys will find actually valuable. Drop your suggestions below 👇 What are you struggling with? What keeps coming up in your research? What would save you hours of digging through forums and Reddit threads? Could be anything: - Specific peptides or compounds - Protocols and stacking - Troubleshooting issues - Vendor evaluation - Testing and quality control - Whatever you're curious about Let me know what would be most helpful and I'll prioritize creating content around it.

Disclaimer: Research peptides only. Educational purposes. Not medical advice. Talk to your doctor. I've always said: research with whatever allows you to stay on plan and keeps you in a deficit. But after experimenting with both extensively, I need to rethink this. My Experience: Tirzepatide → food noise basically gone while still being able to eat Retatrutide + cagri → still thinking about food way too much Even adding cagrilintide to reta hasn't given me the same mental freedom as tirz. And that's making me question whether reta's theoretical advantages are actually worth it for most people. What the Clinical Data Shows: Tirzepatide (SURMOUNT trials): Participants consistently reported serious appetite suppression. Many said they basically stopped thinking about food between meals. Retatrutide (Phase 2 trials): Weight loss was impressive (24% at 48 weeks), but appetite control was hit-or-miss. Some people experienced it, others didn't. The pattern is clear: tirz delivers consistent appetite suppression for almost everyone. Reta is more variable. The Part Everyone Overlooks: Yeah, reta might burn slightly more fat because of glucagon receptor activation. But here's the reality— Most researchers don't have their diet and training dialed in yet. And getting THOSE fundamentals right will do way more for fat loss than reta's glucagon effect ever will. You can replicate reta's fat-burning advantages through: - Increased cardio - Lipo-C injections - L-carnitine supplementation - Fasted training sessions - Consistent resistance training Here's my honest take: If you dial in nutrition, training, and sleep, you'll get comparable results with tirz—without fighting hunger all day. Reta's edge only matters if everything else is already optimized. For most people, it's not. What I'm Seeing: This pattern keeps repeating: researchers switch from tirz to reta, then come back—not because tirz made everything effortless, but because it made staying on plan manageable.