HowSS-31 and MOTS-C fit into the process One of the biggest mistakes people make when starting something like Redatrutide is assuming appetite suppression alone is the solution. In reality, appetite control is only part of the equation. What your cells do with energy matters just as much. This is where mitochondrial optimization comes in. Step 1: Understanding the Foundation From Dr. Sears’ work, one principle comes up over and over again: If the mitochondria aren’t working well, the system downstream doesn’t respond optimally. If someone already feels: - Low energy - Easily fatigued - Metabolically “stuck” - Inflamed or stressed at the cellular level Jumping straight into aggressive appetite suppression can backfire. Calories go down, but energy, recovery, and metabolic flexibility go down with it. That’s why SS-31 is often used first. Phase One: Redatruride + SS-31 Optimizing the engine before changing fuel intake SS-31 works at the mitochondrial membrane level. It’s studied for helping mitochondria produce energy more efficiently and reducing oxidative stress. Think of it as improving how well the engine runs. When SS-31 is introduced before or alongside Redatrutide: - Cells handle lower calorie intake better - Energy production is more efficient - Fatigue risk is lower - The metabolic system feels more stable This phase is especially helpful for people who know their body isn’t optimized yet or who have a history of crashing when dieting. Conceptually: SS-31 helps prepare the system so Redatrutide doesn’t feel like a shock. Phase Two: Redatrutide + MOTS-C Using fuel more intelligently once appetite is controlled Once appetite and food noise are under control with Redatrutide and mitochondrial stress is reduced, MOTS-C becomes a powerful addition. MOTS-C is a mitochondrial-derived peptide studied for: - Improving glucose utilization - Supporting insulin sensitivity - Enhancing metabolic flexibility - Helping the body shift toward fat utilization

Hello everyone so i just recently started MotsC on my second dose but i feel so fatigued tired not what i was expecting. I was expecting just to be full of energy So here is how my 1st cycle i started with SS31 did 4 weeks of 3 mg per day 5 times a weeks for first 2 weeks then did another 2 weeks of 4mg All while doing NAD 3 times a week of 50 mg per day finished ss31 and just started mots on monday at 2.5 mg then did second dose today same and just tired I plan to do 4 weeks of mots 3 times a week 2.5 mg per day. Im still doing NAD 50 mg 3 times a week as well has anyone experienced this on mots?