As you've been exploring peptides, which one made you stop and say, “Wait… what does this actually do?” Share the peptide that initially threw you off—whether it was the mechanism, the dosing, the vial math, or the protocol. For me, I found Epitalon to be the most confusing around 4 years ago. When Russian data came in that challenged our understanding of dosing quantity.

Hi everyone 👋 , This is the space to ask questions, share insights, and swap experiences around your peptide journey and protocols. Common protocol questions revolve around which peptides work most synergistically, optimizing GH protocols, dosing, pulsing, and how to structure protocols for specific outcomes — among many others. Question to kick things off: Which peptides have you been most curious about lately?

I'll start this one off. I got to say, SS-31 is my favorite right now. I had a client recently tell me that she doesn't feel like she needs caffeine when she takes ss-31. Which is literally the whole point!!

Vilon is one of my favorite bioregulators and it really should have more sex-appeal. This is one of the bioregulators. The key synopsis of Vilon is that it works similar to BPC-157 but with slightly different applications and a very different series of mechanisms of action. As usual, stick around for some clinical insights at the end : ) What is Vilon: Vilon is a synthetic bioregulatory peptide (just two amino acids!) originally developed within the Russian peptide research program. Despite its simplicity, it exerts broad effects on immune balance, tissue repair, and cellular resilience. Practically, this means it helps stabilize inflammatory patterns, supports healthier gene expression, and contributes to more efficient recovery and aging processes People use it for everything from calming down skin issues to supporting longevity — and the research behind it is surprisingly impressive for something this small. How Vilon works 1. Immune Regulation Vilon helps recalibrate immune signaling. It modulates cytokine output by decreasing pro-inflammatory mediators (TNF-α, IL-6, IL-1β) and enhancing anti-inflammatory pathways (IL-10, TGF-β). It also improves T- and B-cell function by influencing IL-2 receptor expression, promoting a more efficient and less reactive adaptive immune response. Clinically, this translates to reduced chronic inflammation, better tolerance, and improved immune stability. 2. Gene Expression & Cellular Protection Vilon has documented effects on DNA repair and chromatin structure. It influences histone acetylation/methylation patterns and activates transcription factors such as p53 and FOXO — both strongly associated with cellular longevity, genomic stability, and controlled cell-cycle regulation. This leads to improved tissue repair, enhanced resilience under stress, and healthier aging trajectories. Clinical Pearls Where Vilon tends to shine: - Chronic skin conditions — especially barrier dysfunction, eczema, and inflammatory dermatoses - Systemic inflammation — including low-grade, persistent inflammatory patterns - Pain modulation — due to downstream impact on inflammatory cytokines - Immune balancing — helpful for patients with oscillating hypo-/hyper-immune responses - Longevity support — via genomic stabilization and improved regulatory signaling

Was is BPC 157 that can cause some issues for those with mast cell? Is it best to start with tirzepatide and/or KPV?