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Owned by Awais

Peptide Protocol Academy

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Evidence-Based Peptide Mastery for Optimal Human Performance

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12 contributions to Peptide Protocol Academy
Which peptide has been the most confusing for you to understand?
As you've been exploring peptides, which one made you stop and say, “Wait
 what does this actually do?” Share the peptide that initially threw you off—whether it was the mechanism, the dosing, the vial math, or the protocol. For me, I found Epitalon to be the most confusing around 4 years ago. When Russian data came in that challenged our understanding of dosing quantity.
0 likes ‱ 7d
@Jared Tavasolian great question. I think we continue to learn a lot about Epitalon. But here is a general nutshell 1) supports the pineal immune axis- keeps immune cells in a less reactive state. 2) normalizing effect on T-cells and 3) and improves anti-oxidant pathways.
Post-Anesthesia Mitochondrial Recovery
"I put my mom on 5mg daily for 5 days on, 2 days off because she was having hernia surgery. Anesthesia that can impair mitochondrial activity, and SS-31 can protect against this. She had incredible energy the day after surgery and a beautiful recovery (of course, BPC 157 was part of her pre and post surgery protocol, too!)" -reposted from @Meki Blackwell
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Can peptides help you quit nicotine?
Hiii friends! Happy to be here! I'm wanting to expand my knowledge on peptides and am specifically curious about ones that might be beneficial to someone going through nicotine withdrawals. Alot of people my age got hooked on vapes when they came out and are now struggling to quit... Does anyone have any experience with peptides for addiction?
1 like ‱ 26d
Great Question. I think addiction medicine should be looked at more appropriately. As peptides can be a supportive tool, but a more practical framework and set of tools (accountability, support, etc) can be really important. That being said GLPs like retatrutide microdoses and Tizrepatide moderate doses can be really helpful for curving substance cravings. I've worked with a guy that has struggled with alcoholism for much of his life and tizrepatide 5 mg a week has been absolutely invaluable for him! Not a lot of data for that for nicotine. But my thoughts are reducing the inflammatory burden (with bpc, tb, ghk) and then hitting it with a GLP could potentially be really helpful
0 likes ‱ 9d
@Meki Blackwell Getting to this late but this is absolute gold!! I'm wondering, do you feel the same about nicotine patches? because I find them to be really helpful for lyme/mold patients. And I do love the idea of VIP!
SS-31
I have some ss-31? 20mg - what is a good dosing amount to help with energy?
0 likes ‱ 26d
A standard dose is 2.5 mg to start daily. 5 days on, 2 days off. Though some people pulse it for 30 day cycles. Dosing can be increased to 4 or 5 mg daily if needed. (based on mitochondrial repair needs)
0 likes ‱ 9d
@Meki Blackwell this is so awesome. I am going to post this in the peptide wins section!!
Vesugen: Secret Vascular Gem 
What is it? Vesugen is a Khavinson-style bioregulatory peptide composed of a simple three–amino acid sequence: Lys-Glu-Asp (KED). Here’s the key point. It exerts highly targeted regulatory effects on the vascular endothelium, the microcirculation, and neuronal tissue. And yes it’s good for erectile health. In classic bioregulator fashion, Vesugen appears to restore gene expression patterns in endothelial cells, normalize cellular turnover, and improve tissue resilience under stress conditions. Across animal and human data, Vesugen has been linked to benefits in: - Hypertension - Ischemic vascular conditions - Endothelial dysfunction - Microvascular insufficiency - Age-related cognitive decline  What Do People Feel? Subjectively, Vesugen tends to produce a very recognizable symptom profile. Users commonly report: - More stable energy due to improved microvascular perfusion - Warmth in hands and feet, consistent with enhanced peripheral circulation - Better mental clarity, likely from improved cerebral endothelial signaling - Reduced vascular tension or angina-type tightness - Greater overall vitality, especially in individuals with subtle endothelial impairment Mechanistically, these effects track well: Vesugen supports endothelial nitric oxide balance, reduces low-grade inflammation, stabilizes small vessels, and improves blood rheology. And yes—vascular health = erectile health. Many users notice that Vesugen offers a meaningful boost in erectile function by improving endothelium-driven hemodynamics. Mechanisms of Action (Simplified & Expanded) - Endothelial Gene Expression Normalization Vesugen appears to restore youthful regulatory patterns in endothelial cells—particularly those involved in angiogenesis, vascular tone, and oxidative stress resistance. - Improved Microcirculation By supporting capillary integrity and reducing microvascular inflammation, Vesugen enhances nutrient and oxygen delivery to tissues. - Anti-Ischemic Effects Studies show improved tissue survival and perfusion under low-oxygen conditions, suggesting robust protection against ischemia. - Neurovascular Support The KED sequence has demonstrated unique neurotrophic signaling, helping preserve neuronal health in aging or hypoxic environments.
0 likes ‱ 9d
@Meki Blackwell Yes that is super interesting, that is a great study! we def need more clinical data since this has not been used in the US too much.
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Awais Spall
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13points to level up
@awais-spall-1967
Functional Medicine practitioner & peptide educator teaching regenerative tools for health, performance & longevity.

Active 4d ago
Joined Oct 24, 2025
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