28 OOO replies is higher than I'd normally expect, but I don't think that's the real issue here. What would concern me more is 0 positive replies from ~2,000 sends. That usually points to one (or more) of these: - The ICP isn't a good fit. - The offer isn't compelling enough. - The copy isn't creating enough curiosity or relevance. OOO replies simply tell you the emails are reaching inboxes. I'd spend less time worrying about those and more time reviewing the list quality, segmentation, and messaging. Out of curiosity: - What's your ICP? - What's the offer? - Where did you source the leads from? - How many inboxes are you using, and what's the daily sending volume per inbox?