š§ What the Research Shows - Probiotics, Synbiotics & Thyroid
A recent systematic review & meta-analysis looked at how probiotics and synbiotics affect thyroid function in adults. š Researchers pooled data from 9 clinical trials examining TSH, Free T3 and Free T4 levels. š¬ What they found: ⢠TSH significantly decreased ⢠Free T3 and Free T4 significantly increased ⢠Effects were strongest in: People with existing thyroid dysfunction, Interventions lasting ⤠8 weeks ā ļø Important: This doesnāt mean probiotics ācureā Hashimotoās but this is promising evidence! If youāre dealing with both thyroid autoimmunity and histamine sensitivity, strain selection matters. Here are options that are generally well-tolerated, low in fillers, and commonly used in protocols: 1ļøā£ MegaSporeBiotic by Microbiome Labs Type: Spore-based (Bacillus species) Why itās popular in Hashimotoās protocols: - Shelf-stable soil-based organisms - Minimal excipients - Designed to support gut barrier integrity š” Best for: Those wanting strong microbiome modulation without common histamine-producing strains. ā ļø Start low and go slow if highly histamine sensitive. 2ļøā£ Biospora (by Klaire Labs) Type: Spore-based Why it fits: - Clinically used - Minimal fillers - Often well-tolerated in autoimmune protocols š” Best for: Thyroid autoimmunity + histamine intolerance. 3ļøā£ VitaMonk Low Histamine Probiotic (by VitaMonk) Type: Lactobacillus & Bifidobacterium blend Why it fits: - Designed to avoid histamine-producing strains - Focused on histamine-neutral support š” Best for: Those with strong histamine reactions who canāt tolerate many standard probiotics. š§ Important Reminder Not everyone with Hashimotoās needs probiotics. Before starting: - Assess gut symptoms (bloating, constipation, loose stools, reflux) - Consider iron status (low iron is common in thyroid dysfunction) - Evaluate stress load (cortisol impacts gut + thyroid signaling) Probiotics work best as part of a bigger strategy: āļø Blood sugar stability āļø Nutrient density (especially heme iron, selenium, zinc)