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Owned by Curtis

The Healing Path

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Ask anything. Learn everything. Education on complex chronic illness, hormones, peptides, gut health, CIRS, Lyme, you name it.

The Blu≡Prnt Collective

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Skoolers

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157 contributions to The Healing Path
Returning to boxing at 40 — stacking nootropic peptides + injectable L-carnitine for reaction time and fast-twitch. Looking for evidence and protocol input
Coming back to boxing at 40. Reaction time, fast-twitch recruitment, and how fast I pick up skills have all slowed down, and I want to attack that directly with a compound protocol. The stack: Dihexa, Noopept, CMS121, and Semax for neuroplasticity, motor learning, and reaction time, plus intramuscular L-carnitine for recovery and fast-twitch support. I dont care about a safe approach, just go hard lol. - How would you time each one around training and sparring? Semax and Noopept are short-acting, so I assume dosing windows matter — before skill work, after, both? - Dihexa dosing and where it fits — daily baseline, or loaded around heavy learning blocks? - CMS121 — dose and timing you'd actually use. - IM L-carnitine — dose, injection frequency, and timing relative to training. - Stack order and any interactions between these worth knowing. - If you were going all-out on performance, what does your full protocol look like day-to-day? - Performance-first, I know what I'm doing and I'm committed to the approach — just looking to optimize the timing and dosing. Firsthand experience especially welcome.
@Weissam Eid What are you doing for fuelling and recovery? Those are going to matter more than that protocol, and they will most likely dictate how that protocol goes. Adding more boost to your engine (from your turbocharger, for those who are not mechanically inclined lol) without supplying more fuel or upgrading your fuel system (improving gut health) is asking for your engine to pop, and if you don't have the latest and greatest emissions system, the government will throw you in jail. I don't know, I am terrible at analogies 😂 Everything mentioned other than the CMS-121 is going to increase the demand for fuel and antioxidants. Without that, you will create more reactive oxygen species and more inflammation (it may not be right away, but over time, "athlete burnout"; I should have a good testimonial soon of correcting that in an athlete), and it will be harder to improve what you're looking for. Quality sleep would outrank all of these. Oxygen consumption/liberation and CO2 tolerance would also come before these. DIHEXA is more of a restorative compound. It has never been shown to increase performance past baseline, and it wouldn't have much to do with reaction time. Semax and Noopept would potentially help increase reaction time. The acetyl form of carnitine MAY be better suited in the context of reaction time as it can cross the blood brain barrier, but otherwise there is 0 evidence that it improves reaction time directly. CMS-121 would not improve reaction time directly either, but it could improve recovery. Your neurotransmitters are going to play the largest role here, so that's why the Semax and Noopept would have the most affinity for reaction time. But if you don't have the necessary substrate to fuel those neurotransmitters, it'll just bog you down, and it'll be harder to increase reaction time and improve skill. Carnitine would help with mitochondrial fuelling, which could increase performance, and that also could increase your ability to produce neurotransmitters. Once again, you need the necessary substrate. This is where B vitamins come in, especially ones like vitamin B6. You also need B1, B3, B5, alpha lipoic acid and B12 to fuel the Krebs cycle/mitochondria.
August 08-26 Live Q&A Recording
Hey everyone, Here is the recording from today's Q&A! https://www.skool.com/the-healing-path/classroom/16bfed01?md=ce00248bda6746c9b12416185578c20a (4:13 – 13:35) Danielle's Husband John — Nystatin, Clostridia, and the Kidney Connection • Avoid hammering an assumed infection — aggressive antimicrobials disrupt the microbiome, drive inflammation, and generate toxic byproducts the liver and kidneys can't keep up with, which matters especially given John's kidney picture • Slow single-ingredient approaches (caprylic acid, or oil of oregano which is stronger) are the gentler route, but nystatin takes priority here because it destroys ergosterol, the yeast cell membrane — like poking a hole in a bucket, the organism physically cannot survive without it • Fluconazole works differently, entering the yeast cell to inhibit ergosterol formation; medications act far faster than botanicals, which matters when the goal is reducing an immune response quickly in rheumatoid arthritis • Clostridia is worth considering if nystatin doesn't produce the expected improvement — Candida and Clostridia go hand in hand, though Curtis leans yeast for John since Clostridia would likely produce more neurological presentation • Foam in the urine is a kidney signal; Dan Shen, Rehmannia, and astragalus support the kidneys, but the infection still has to be cleared or it's an uphill battle • Beta-glucuronidase (raised by yeast) recycles toxins back into the system — bile packages a toxin like a tied garbage bag in the small intestine, and beta-glucuronidase unties the bow further down; this is why some people show clean stool markers while nothing is actually leaving the body • Yeast also causes translocation into the blood, which puts the load back on the kidneys • Sourcing options for nystatin and fluconazole: Push Health (US, often covered by insurance and prescribing 90-day supplies), All Day Chemist, or a sympathetic local prescriber — aim for at least 90 days, not the standard two weeks
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Drop your questions here for tomorrow's Q&A!
Hey everyone, If you can't make the Q&A tomorrow, go ahead and drop your questions in the comments below. I'll do my best to cover them live on the call, and anything I don't get to I'll follow up on afterward, either by replying here on the thread or recording a quick Loom video.
Protecting Your Heart Guide
Hey everyone, Heart disease is a leading cause of death in North America. I just posted a new guide on how to prevent heart problems before they start. If you use anabolic steroids, this guide is especially important for you. The guide covers blood pressure, exercise, and sleep as the first steps, followed by diet, and then which supplements and herbs are actually helpful. There are over twenty options with recommended doses, plus advice on what not to combine. It also lists the tests you should ask your doctor about. https://www.skool.com/the-healing-path/classroom/a80be44b?md=e5b5325c8b094f45888833360a14ef7e
@Shannon Segerstrom Does he have labs?
@Mackenzie Field 🙌
2 Dog Questions
1️⃣ one of our pups (black and white) itches like crazy - paws, face, and will scratch behind her ears. The vet uses apoquel but she’s only 3.5 years old so I hate to do that. 2️⃣ other pup’s (white and tan) right ear is red, stinks, itches. We clean it and brown goo comes out. I clean it with 50/50 alcohol and water. She dreads the cleaning, but she is so happy afterwards and loves it then.
2 Dog Questions
@Kalee Dillard haha yeah I was going to forward you that email but then I figured you would have already seen it 😂
@Shannon Segerstrom I don't see why all dogs couldn't take it! I usually recommend against poultry for dogs, it's one of the most common known allergies/intolerances. This site is new so I have no experience but the creator is a chemist, very intelligent. https://4leggedlongevity.com/store
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Curtis Gillespie Sayers
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@curtis-gillespie-sayers-2930
Guiding people to restore balance and vitality through functional medicine, lifestyle optimization, and targeted healing.

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Joined Mar 7, 2026
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