Hey everyone, Here is the recording from today's Q&A! https://www.skool.com/the-healing-path/classroom/16bfed01?md=ce00248bda6746c9b12416185578c20a (4:13 – 13:35) Danielle's Husband John — Nystatin, Clostridia, and the Kidney Connection • Avoid hammering an assumed infection — aggressive antimicrobials disrupt the microbiome, drive inflammation, and generate toxic byproducts the liver and kidneys can't keep up with, which matters especially given John's kidney picture • Slow single-ingredient approaches (caprylic acid, or oil of oregano which is stronger) are the gentler route, but nystatin takes priority here because it destroys ergosterol, the yeast cell membrane — like poking a hole in a bucket, the organism physically cannot survive without it • Fluconazole works differently, entering the yeast cell to inhibit ergosterol formation; medications act far faster than botanicals, which matters when the goal is reducing an immune response quickly in rheumatoid arthritis • Clostridia is worth considering if nystatin doesn't produce the expected improvement — Candida and Clostridia go hand in hand, though Curtis leans yeast for John since Clostridia would likely produce more neurological presentation • Foam in the urine is a kidney signal; Dan Shen, Rehmannia, and astragalus support the kidneys, but the infection still has to be cleared or it's an uphill battle • Beta-glucuronidase (raised by yeast) recycles toxins back into the system — bile packages a toxin like a tied garbage bag in the small intestine, and beta-glucuronidase unties the bow further down; this is why some people show clean stool markers while nothing is actually leaving the body • Yeast also causes translocation into the blood, which puts the load back on the kidneys • Sourcing options for nystatin and fluconazole: Push Health (US, often covered by insurance and prescribing 90-day supplies), All Day Chemist, or a sympathetic local prescriber — aim for at least 90 days, not the standard two weeks