This is the first thing I'd love you to do when you join. Reply below and tell us: 1. Your variant: C677T, A1298C, compound heterozygous, or not yet tested? 2. What brought you here: what's your biggest question or health concern right now? 3. One thing you're hoping to get from this community 4. Every reply gets a personal response from me. This is not a number on a member's list; you are a person with a real health story, and it matters. I'll go first 👇 As a physician, I became interested in methylation after observing several patients who did not improve with standard protocols. I saw a gap in how I cared for patients. This prompted me to study genomics and nutrigenomics, with a focus on MTHFR and how minor genetic variations affect health. As I learned about MTHFR's clinical relevance, similarities between my patients, my personal medical history, and the condition led me to undergo genetic testing. I found that I am heterozygous for the MTHFR 1298 T>C variant. This underscored the importance of genetics in clinical practice and changed the way I support patients, especially those who do not respond to standard protocols. I now ensure my diet includes ample folate-rich foods and, as needed, supplements. After 25 years in practice, I am convinced that identifying key genetic factors is essential for effective patient care, helping me focus on meaningful interventions and avoid unnecessary complexity.