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Built With // MS

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Life is Built through movement, nutrition, purpose, and community. Show up daily, build better habits, and discover what you're capable of.

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15 contributions to BioOptimization Collective
Poll Results On Longevity Peptides
Mots-C received the most votes. Then #2 was Epitalon. #3 GHK-CU and #4 SS-31. Most people accept aging as inevitable. The science increasingly does not. What we call aging is a measurable cascade of cellular events. Mitochondrial decline. Telomere shortening. Collagen breakdown. Chronic inflammation that never fully resolves. These are not mysteries. They are addressable biological processes. And four compounds in the current research literature are targeting each one of them directly. MOTS-c — Your Mitochondria Have a Longevity Signal. Here Is How to Restore It. Identified in 2015 by researchers at USC and published in Cell, MOTS-c is encoded directly in mitochondrial DNA and activates AMPK — the same metabolic switch triggered by fasting and exercise. Published research shows improved insulin sensitivity, enhanced fat oxidation, and increased endurance in study models. A 2019 study confirmed MOTS-c levels decline significantly with age in humans, correlating directly with metabolic dysfunction and reduced physical capacity. This is not a synthetic compound mimicking a natural process. It is the natural process itself, restored. Epitalon — The Only Compound Shown to Activate Telomerase in Human Cells Every cell division shortens your telomeres. When they get short enough cells stop dividing and begin secreting inflammatory signals that accelerate aging in surrounding tissue. That process is called cellular senescence and it is one of the primary drivers of age-related disease. Epitalon, developed by Dr. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, has demonstrated telomerase activation in human somatic cells in peer-reviewed research published in Neoplasma. It has also shown restoration of melatonin rhythms, improved immune function, and in long-term studies a statistically significant extension of lifespan. Over 35 years of research and more than 100 published studies back this compound. That is not a claim. That is a track record.
1 like • 17d
@Victor Ortega 100%. I felt the same way on SS31. I just had to make a decision my self what to focus on and I went inflammation reduction and metabolic health focus first with the stack I’m on. Might go back to SS31… maybe during winter when it’s grey and cold :)
0 likes • 17d
@Victor Ortega mitochondria right now 😂
The 5 Most Promising Peptides for Longevity and Performance in 2026
The world of peptides is evolving fast. Every week, new compounds are being discussed in biohacking groups, longevity communities, and performance circles. Some are overhyped. Some are poorly understood. And a few may genuinely change the future of human health and aging. After reviewing the latest discussions and research trends, these are the five peptides that have captured the most attention from scientists, clinicians, and biohackers alike. 1. Retatrutide: The Next Generation Fat Loss Peptide Many experts believe Retatrutide could eventually outperform both Semaglutide and Tirzepatide. Why? Because it targets three metabolic pathways instead of one. Potential benefits include: Significant fat loss Improved insulin sensitivity Better metabolic health Reduced cardiovascular risk This may become one of the most important metabolic therapies of the next decade. 2. MOTS-c: The Exercise Mimetic What if your cells could act as if they had exercised? MOTS-c is a mitochondrial peptide that appears to improve energy production, metabolic flexibility, and physical performance. Researchers are studying its role in: • Healthy aging • Metabolic health • Mitochondrial function • Exercise performance For longevity enthusiasts, this is one of the most exciting peptides currently being explored. 3. Humanin: Protecting Your Cells From Aging Humanin is another mitochondrial-derived peptide that may help protect cells from age-related decline. Potential benefits include: Neuroprotection Reduced inflammation Improved cellular resilience Support for healthy aging As we learn more about mitochondria and longevity, Humanin continues to gain attention. 4. SS-31 (Elamipretide): Mitochondrial Repair Most age-related diseases involve mitochondrial dysfunction. SS-31 is designed to target and improve mitochondrial efficiency. Researchers are investigating its potential for: • Heart health • Energy production • Muscle performance • Healthy aging Of all the peptides currently being studied, SS-31 may have some of the strongest scientific backing.
1 like • Jun 24
What a list! The problem is picking what stack to b use together as there is seemingly a peptide for most things you could want.
Monday Doesn’t Care How You Feel. Show Up Anyway
Monday is a fresh opportunity to become the person you were created to be. You don’t need all the answers. You just need to take the next step. Start with gratitude. Move your body. Feed your mind. Love your people. Then get to work. The life you want is built one decision at a time. One workout at a time. One day at a time. This week, choose discipline over excuses. Choose faith over fear. Choose action over procrastination. A year from now, you’ll either be grateful you started today or wishing you had. Show up. Work hard. Keep your word. Let’s make this week count.
1 like • Jun 22
Hell yes! It just takes one step to create momentum.
Can Only Pick One
If you had to choose just one peptide for the rest of your life, which would you pick? Mine would be Ipamorelin which supports the body's natural growth hormone production, promotes recovery, helps maintain lean muscle, improves sleep quality, and supports healthy aging without replacing the body's own hormones.
1 like • Jun 11
Tough question! I use a stack which I like but if I had to choose one I’d say BPC-157. Seem great results with tissue repair plus inflammation reduction which is great for MS.
Peptides Won’t Fix a Broken Lifestyle… But They Can Optimize a Disciplined One.
Everyone wants the shortcut. Fat loss. More muscle. Better recovery. More energy. Anti-aging. That’s why peptides are exploding in popularity. But here’s the truth most people don’t want to hear: Peptides are amplifiers — not replacements. They can help improve: - recovery - sleep - metabolism - inflammation - muscle preservation - healing - performance …but they work best when combined with: - quality sleep - training - nutrition - hydration - stress management - consistency The people getting the best results aren’t looking for magic. They’re building a lifestyle. Because real optimization isn’t about doing one extreme thing… It’s about doing the right things consistently long enough for your body to finally work the way it was designed to. When that happens: - energy changes - confidence changes - performance changes - recovery changes - life changes The goal isn’t perfection. The goal is becoming stronger, healthier, more disciplined, and more capable year after year.
3 likes • May 27
It’s so true. If you do t change your lifestyle, you’ll never really get the results you want.
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Adam Koller
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@adam-koller-3821
Changed my life with MS. You can change yours too no matter what you're building with. Start the 7-Day Reset: BuiltWithMS.com

Active 22m ago
Joined Nov 11, 2025
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