For men on active surveillance — a urine test that could cut 64% of unnecessary biopsies
This one is specifically for community members who are in the active surveillance phase, or who have a family member in it.
New research published this week in the Journal of Urology evaluated a urine-based test called MPS2-AS in more than 300 men with low-grade prostate cancer being monitored on active surveillance.
The results:
— 97% sensitivity for detecting high-grade cancer (Grade Group ≥3)
— 99% negative predictive value for cancer upgrading
— Would have avoided 64% of unnecessary biopsies while still catching every cancer that needed treatment
For men who've been through the repeat biopsy cycle — you know what that routine costs. Not just physically. The weeks of waiting before and after. The mental load of not knowing. The effect on the people around you.
This test doesn't replace the monitoring conversation with your urologist. But it gives that conversation a new tool — one that might mean the biopsy only happens when there's a real reason.
Currently the study only covers 300 men, but the results are very encouraging. Watch this space.
Is anyone here in the active surveillance phase? Or supporting someone who is? I'd love to hear what the monitoring cycle has actually been like — the research is important, but your experience matters more to this community.
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For men on active surveillance — a urine test that could cut 64% of unnecessary biopsies
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