What to Actually Expect When Cycling Off GH Secretagogues (Week-by-Week)
Who this is for:
  • Anyone currently researching ipamorelin, CJC-1295, Tesamorelin, or any GH secretagogue
  • People planning their first peptide research cycle and wondering about the off period
  • Researchers who think "more is better" and never cycle off
  • Anyone nervous about what happens when they stop
What you'll learn:
✅ Week-by-week breakdown of what to expect (energy, sleep, recovery, body comp)
✅ Why receptor desensitization ISN'T the real reason to cycle (despite what everyone says)
✅ The actual mechanism that matters: chronic IGF-1 elevation and what it means long-term
✅ How lifestyle factors (training, cardio, diet) protect you—and when they're not enough
✅ Exact bloodwork markers to track and testing frequency (quarterly vs. bi-annual)
✅ Data-driven cycling protocols based on YOUR numbers, not generic advice
The hard truth: Most people researching GH secretagogues have never checked their IGF-1 levels. They don't know if they're at 250 or 450. They're making decisions blind.
This article breaks down the science, the timeline, and the practical protocols—no BS, just data on what actually happens when you come off.
Drop questions below after reading. Let's talk real protocols based on real bloodwork. 📊
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Derek Pruski
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What to Actually Expect When Cycling Off GH Secretagogues (Week-by-Week)
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