Thymulin vs. Thymosin Alpha-1 β€” what's the difference? 🧬
If you've looked into thymic peptides, you've probably seen both of these come up.
Same gland. Both "immune peptides." Must be pretty similar, right?
Not even close.
These two work through completely different mechanisms:
β†’ One works directly on T-cells and requires zinc to function β†’ One activates dendritic cells through toll-like receptors
β†’ One has major neuroendocrine crossover β†’ One bridges innate and adaptive immunity
β†’ One crashes hard with age (often undetectable by 60) β†’ One is approved in 30+ countries with extensive clinical data
Knowing the difference matters if you're researching either one.
Broke it all down in the new Substack β€” the mechanisms, what each one actually does, and when one might make more sense than the other.
Drop any questions below πŸ‘‡
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Derek Pruski
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Thymulin vs. Thymosin Alpha-1 β€” what's the difference? 🧬
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