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Oct '25 (edited) • Peptide Tips
🧬 Tesa/Ipa or CJC/Ipa? The Ultimate GH Stack Comparison
The Battle of the Blends 👀
Great question that comes up all the time. Let me break down both stacks so you can decide which fits your goals better.
🧬 THE PEPTIDES
Tesamorelin (Tesa)
- GHRH analog (growth hormone releasing hormone)
- Shorter half-life (~30 minutes at the receptor)
- More pulsatile GH release
CJC-1295 (without DAC)
- GHRH analog (growth hormone releasing hormone)
- Short half-life (~30 minutes)
- Pulsatile GH release, very similar to Tesa
Ipamorelin (Ipa)
- GHRP (growth hormone releasing peptide)
- Ghrelin mimetic
- Amplifies GH pulses
- Used in BOTH stacks
⚔️ HEAD TO HEAD COMPARISON
TESAMORELIN/IPAMORELIN
Benefits:
✅ Specifically targets visceral fat (FDA-approved for lipodystrophy)
✅ Strong fat loss properties, especially abdominal/organ fat
✅ Natural pulsatile GH release
✅ Well-studied with clinical data
✅ Less bloat/water retention reported
Downsides:
❌ More expensive than CJC
Best for:
- Fat loss focused researchers (especially stubborn belly fat)
- Body recomposition
- Those with access and budget for it
- People who want the most clinically studied option
Typical dosing:
- Tesa: 1mg-2mg per day
- Ipa: 100-300mcg 1-3x per day
CJC-1295 (No DAC)/IPAMORELIN
Benefits:
✅ More affordable than Tesa
✅ Easier to source consistently
✅ Natural pulsatile GH release (same as Tesa)
✅ Great for recovery and muscle growth
✅ Improves sleep quality
✅ Good all-around GH optimization
Downsides:
❌ Not as targeted for visceral fat loss as Tesa
❌ Some report more water retention
Best for:
- Recovery and healing
- Muscle growth and performance
- Sleep improvement
- Budget-conscious researchers
- Long-term GH optimization
Typical dosing:
- CJC (no DAC): 100-300mcg 1-3x per day
- Ipa: 100-300mcg 1-3x per day
🎯 THE REAL DIFFERENCE
Here's the truth: Both stacks work very similarly because CJC (no DAC) and Tesamorelin have nearly identical half-lives and mechanisms.
The main differentiator is Tesamorelin's specific action on visceral adipose tissue. If fat loss (especially stubborn belly fat) is your primary goal, Tesa has the edge.
For everything else - recovery, muscle growth, sleep, anti-aging - they're extremely comparable. CJC/Ipa gives you 90% of the same benefits at a better price point.
💡 MY TAKE
Choose Tesa/Ipa if:
- Fat loss is your #1 priority
- You want the most clinically studied option for body composition
- Budget isn't a concern
Choose CJC/Ipa if:
- Recovery, performance, and overall GH optimization are your goals
- You want better value for money
- You're running this long-term
The honest answer? You can't go wrong with either. Both create natural GH pulses when dosed together. The Ipa is the same in both stacks - it's really just Tesa vs CJC (no DAC), and they're more similar than different.
What are you running and why? Drop your experience below! 👇
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🧬 Tesa/Ipa or CJC/Ipa? The Ultimate GH Stack Comparison
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