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Oct '25 (edited) • Peptide Tips
L-Carnitine: The Mitochondrial Shuttle for Fat Oxidation 🛸🚀
Today's Deep Dive: L-Carnitine
THE MAIN JOB: FAT TRANSPORT
Your mitochondria produce energy. They can burn glucose or fat, but there's a problem:
Fat molecules are too big to enter the mitochondria on their own.
L-carnitine is the shuttle that carries fat across the mitochondrial membrane.
The Process:
- CPT1 enzyme attaches a fat molecule to carnitine outside the mitochondria
- This complex crosses the membrane (something fat can't do alone)
- CPT2 enzyme releases the fat inside where it gets burned for energy
- Free carnitine goes back out to grab another fat molecule
No carnitine = fat stuck outside your cells Optimal carnitine = fat getting burned
CLEARS METABOLIC WASTE
During intense training or fasting, acetyl-CoA builds up in your mitochondria. This buildup blocks energy production—like a traffic jam.L-carnitine binds to these acetyl groups and removes them, keeping your energy systems running smoothly.This is why it helps during fasted training or on low-carb diets.
IMPROVES INSULIN SENSITIVITY
By burning fat inside muscle cells, carnitine prevents fat accumulation in the muscle tissue.
Fat buildup in muscles interferes with insulin signaling. Less fat in the muscle = better insulin response = better nutrient partitioning.
Translation: More of what you eat goes to muscle, less to fat storage.
INCREASES BLOOD FLOW
L-carnitine boosts nitric oxide production, which dilates blood vessels.
More blood flow = more oxygen and nutrients to muscles + better waste removal.
BRAIN SUPPORT (ALCAR Specifically)
Acetyl-L-carnitine crosses into the brain and:
- Provides building blocks for acetylcholine (memory/focus neurotransmitter)
- Protects neurons from oxidative damage
- Supports mitochondrial function in brain cells
WHY YOU MIGHT BE LOW
Your body makes carnitine from lysine and methionine, but needs:
- Vitamin C, B6, B3
- Iron
If you're deficient in any of these, production drops.
Also:
- Vegans get almost no dietary carnitine (it's in red meat)
- Production declines with age
- Certain genetics limit synthesis
THE BOTTOM LINE
L-carnitine removes bottlenecks in your fat-burning machinery.
It won't burn fat if you're not in a deficit. It won't build muscle without training.
But if you're already training hard and eating right, it optimizes the system you're already using.
Research Dosing: 200-500mg per day Frequency: Daily Timing: Pre-workout on training days (30-60 min before) OR first thing in the morning on rest days Injection site: Intramuscular (deltoid, glute, or quad) OR subcutaneous (abdomen, love handles)
Drop Questions Below 👇
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L-Carnitine: The Mitochondrial Shuttle for Fat Oxidation 🛸🚀
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