Dr. Ty, I am currently on trt and tirzepatide, do you have any recommendations for peptides that can optimize weightloss and help me save muscle.

I’m 45, on TRT and nandrolone. After increasing my TRT dose about a month ago, sensitive estradiol jumped to 181 (from 46) and total estrogen reached 473 (first time testing). I’m one week into a 30 day rosuvastatin trial for reducing LDL (128) and ApoB (108) at 10 mg and have been holding anastrozole so I can isolate the statin’s overall impact. My concern is that starting both could create overlapping fatigue or joint pain and be hard to isolate which is causing what. No current side effects or issues. Wondering if I should start the AI now or is waiting another three weeks reasonable (verify rosuvastatin impact, if any and run blood work)? Thank you.

Have you been put on testosterone… and still feel like something's missing? If that's you, I want you to know why, because I inherit a lot of women from other practitioners, and they almost always have the same thing missing. They came in tired, foggy, no drive, not healing well. Their doctor saw a low testosterone number and did the "obvious" thing: loaded them up on testosterone. Now they've got some facial hair and acne to show for it… and they still don't feel right. Here's what almost nobody told them: in a woman, the foundational androgen isn't testosterone. It's DHEA. Women only need a fraction of the testosterone men do, so DHEA quietly does the heavy lifting for strength, energy, focus, resilience, and your ability to heal and repair. And here's the part that changes everything: almost all of a woman's testosterone is made from DHEA in the first place. Give a woman the right amount of DHEA, and her body can build the testosterone she needs from it, the math is massively in her favor. So why does everyone skip it? Because DHEA is cheap and available over the counter. The compounding pharmacies that train most practitioners can't sell it to you at $300 a month, so it barely gets a mention. I sat in those seminars. I watched it happen. A few things I get into in this video: → Why "estrogen dominance" can happen at a normal estrogen level (it's about balance, not the number) → Why I give most postmenopausal women progesterone and DHEA without even testing → How I optimize DHEA first, then reassess, and the ~20% of women who genuinely need testosterone added → Why the same lab number means completely different things in different bodies The one line that I always come back to: your symptoms and your story come first. Two women with the identical number can need completely different things. Optimize the foundation, and the whole picture changes. 💬 So let me ask you: have you ever been handed a hormone and told "this is the fix," only to feel like it wasn't the whole story? Tell me in the comments, I read and answer every single one.