Specimen Processing: Why Hemolysis Happens (And How To Prevent It)
Let’s talk about something that shows up a lot on the exam — hemolysis.
Hemolysis means the red blood cells break open. When that happens, the specimen may not be usable.
On the NHA exam, you may see a question like:“A specimen was rejected due to hemolysis. What most likely caused this?”
Here are common causes:
  • Using a needle that is too small
  • Pulling the syringe back too fast
  • Shaking the tube instead of gently inverting
  • Forcing blood from a syringe into a tube
  • Drawing from a site with a hematoma
Now let’s talk prevention:
  • Use the correct needle size
  • Allow tubes to fill naturally
  • Gently invert — do not shake
  • Follow proper collection technique
  • Release the tourniquet within 1 minute
Remember this:
If the specimen is damaged, the results are not accurate.If the results are not accurate, the patient may receive the wrong treatment.
Specimen processing is not just about handling tubes. It is about protecting patient care.
Make sure you understand why hemolysis happens — not just the definition. That is how you pass scenario-based questions.
Stay consistent. Module 5 is building your professional habits.
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Cherell Evans
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Specimen Processing: Why Hemolysis Happens (And How To Prevent It)
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