Growth Hormone Peptides 101
I posted this over in the paid community, but wanted to share over here as well. We also have an All Things Growth Hormone Course in the classroom over there that breaks down a lot of components surrounding Growth Hormone and the secretagogues - Hey everyone! I wanted to put together a quick overview on GH peptides since this comes up a lot. There's a fair amount of confusion around how they work, what to stack, and what to actually expect, so here's an overview of the main questions. Also, I will be pinning this post into the All Things Growth Hormone Course. Growth Hormone peptides fall into two main categories. The first is the GHRH analogs like Sermorelin, CJC-1295, and Tesamorelin. The second is the GHRPs, also called ghrelin mimetics, like Ipamorelin, GHRP-2, GHRP-6, and Hexarelin. This is important to understand: BOTH of these categories push your pituitary gland to release growth hormone, but they essentially take different roads to get there. GHRH peptides bind to the GHRH receptor, which is the body's normal "release GH" signal. GHRPs bind to a completely separate receptor called the ghrelin receptor, which will also lead to GH release but through a different pathway. So like I mentioned before, you're getting to the same destination, but taking different routes. Any of these peptides can be taken alone. You don't HAVE to stack to get results, and plenty of people run something like sermorelin or ipamorelin by itself and see exactly the results they want. It is important to note though that the GHRPs can stimulate appetite, so any time you add one, you may feel that happening. So if that's a concern, ipamorelin by itself wouldn't make much sense. So if you're just starting out, you can definitely just pick one of them. Now, here's why stacking can be beneficial... The classic combo is to add a GHRH with a GHRP because they're hitting two different receptors that both lead to GH release. When you stimulate both pathways at the same time, you're basically giving synergy to what they can do to ultimately get better results. You get a bigger GH pulse than either peptide could produce on its own.