@Stephanie Lukaszka the highest I ever went with TRZ was 7.5; hit a plateau after about 75-80lbs lost. Added in a little Reta out of curiosity. Wow! Certainly the glucagon awakened my appetite; however after two weeks with just a mg added to my weekly T (3.5 days apart), the stall broke. Later switched just to R—going from 2mg to 4mg over a few months, but lost the benefits T gave me (off HBP, thyroid, arthritis meds). Started back on T with a tiny dose of each (R also) 3.5 days apart. Since I am dabbling with maintenance after 115# loss, I generally just do 1-2mg weekly depending upon how everything varies. Halloween marks 2 yrs since I began, so I benefited in many more ways than just weight loss. I also am flexible with my pins only after a complete (TMI WARNING) & thorough trip to the loo! With inflammatory bowel disease, I must be clean or no shot, so flexibility for me is a must. Recently went 10 days without pinning— prior to endoscopies & gained a little. My original goal was 115 (I am short), but at 125, I am happy & thankful! Hope this helps. Micro-dosing DOES have more “precise” terms, but it’s a given THAT we all know we are talking about a few times a week in smaller dosages.

And I really don’t listen to the naysayers about receptors burning out and “why combine”, as I know my research (3 grad degrees) has not steered me wrong!

@Dawn Moser Go to YT & watch Hunter Williams’ recent educational breakdown on Mel 1 & 2. He explains it so well. Mel1 is one of my favorites & we use Mel2 for my hubs. They have differences, including that 2 helps ED, but both do help the libido as well as tanning. PT-141 is a spin off of this amino. All 3 are great; M1 is slow & steady while M2 is more short-term. But Hunter explains much better than I. Go watch; you’ll be glad you did!

Start at 2mg & be ready to eat! The appetite will come back due to glucagon / amylin; however, about 1 month in, your rat will still have an appetite, but will be FULL after 2-3 bites. Here I dabbled with R to break plateaus; then, went all R. After inflammation showed its ugly face again, I decided to micro-dose both T & R. & although there’s lots of naysayers, it works for my TS! From 237 to 122 & use T on Sun morning & R on Tues pm. Don’t care 🤷‍♀️ what the naysayers say, maintenance is great with a tiny bit of both!