Anxious about raising urea and creatinine
Age + Condition 55M, Nodular Glomerulosclerosis with nephrotic proteinuria. Previously BP and sugar uncontrolled but now controlled. Key numbers (BP, creatinine/eGFR, ACR, HbA1c) Bp - 140/80 ACR: 5654 mg/g (A3 severe proteinuria) Creatinine: in January 1.9 urea 42 After fenofibrate + rosuvastatin (prescribed by my nephrologist to lower uacr)โ Creatinine 2.8, Urea 60 in February After stopping fenofibrate for 1 week โ Creatinine 2.3, Urea 45 Now on atorvastatin 80 mg โ Creatinine 2.82, Urea 72 ( in march ) Potassium: 5.69 Phosphorus: 5.54 Sodium: 140 Current medicines Alpha ketoanalogue, dapagliflozin, nefrosave, atorvastatin 80 mg. 1-line question Lipid profile mostly normal (HDL slightly low). Since statins/fenofibrate seem to increase creatinine and cause stomach irritation, are high-dose statins still necessary in CKD with heavy proteinuria? Feeling Confused and anxious.