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2 contributions to GLP-1 & Peptide Clarity Group
Thanksgiving on a GLP-1?
Thanksgiving on a GLP-1? You can enjoy the day without ending the night in a food coma or... guilt. 🦃✨ My simple game plan: - Lead with protein + veggies. - Go easy on the heavy hitters. Be mindful of fatty/greasy foods - your belly will thank you later! - Hydrate more than you "drink." My trick - a glass of water between a bevvie - Take a mid-plate pause. - Choose your treats on purpose. One holiday won’t make or break your progress—but how you treat your body (and talk to yourself) does matter. 🧡 Happy Thanksgiving Fam! For educational purposes only. Not medical advice.
Thanksgiving on a GLP-1?
0 likes • Nov 26
Everyone needs this!! 🦃
Tirz vs Reta: The Showdown
The “King of GLP-1s” Debate — My Honest Take I get this question constantly: “Is Retatrutide the new King of GLP-1s?” My answer? It’s not that simple — and it’s definitely not for everyone. Retatrutide adds a third hormone, glucagon, which can boost metabolism and energy expenditure. Tirzepatide (Mounjaro/Zepbound) works primarily on GLP-1 and GIP, which are powerful for appetite regulation and glucose control — but the added glucagon in Retatrutide can change the experience. Here’s what that can mean: - 🔥 Metabolism boost: Retatrutide may increase calorie burn. - 🍽️ Slightly less appetite suppression: Because you’re burning more, your body may feel less “satisfied” than with Tirzepatide. - ⏳ Slower onset: Many users find that appetite suppression takes longer to kick in. - ⚖️ Weight loss differences: Clinical data and anecdotal reports suggest results may appear at higher doses of Retatrutide compared to lower doses of Tirzepatide. My Personal Experience I’ve been microdosing Tirzepatide (2 mg/week) since mid-May and lost about 30 lbs. Recently, I decided to test Retatrutide (0.5 mg/week) as a way to maintain weight loss while focusing on building lean muscle — since my appetite was so low I wasn’t eating enough to fuel my workouts. My first dose of Retatrutide hit me hard: Within hours, I experienced hot sweats and a racing heart that triggered anxiety. I took two weeks off and tried again — but the same thing happened. At a family dinner, I suddenly became dizzy, flushed, and had to step outside to catch my breath. (At 41, I wondered if it was perimenopause — but I’m pretty sure it wasn’t.) So if you’re considering switching, especially if you have any heart concerns or anxiety, start low and slow — and always with medical supervision. Key Takeaway Every GLP-1 therapy works a little differently for every body. Tirzepatide has been steady, predictable, and effective for me; Retatrutide may have incredible potential for others — but it’s more complex and still being studied.
Tirz vs Reta: The Showdown
0 likes • Nov 5
Thanks for sharing. I'm about to graduate to Reta after being stalled on Tirz weight loss for the past few months.
0 likes • Nov 5
@Jessica Delguercio I don't think that appetite is the issue. I feel that I do an OK job keeping that in check. I'm just frustrated that I'm going to the gym 5x per week and taking heavy dosages of Tirz and I'm just stuck at the same weight.
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Jeff Mendelson
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@jeff-mendelson-9970
Automations Superhero 🦸

Active 13h ago
Joined Nov 2, 2025
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Fort Lauderdale, FL