ApoB is one of the most useful cardiovascular markers because it gives us a better estimate of the **number of atherogenic lipoprotein particles** circulating in the blood. That includes particles such as LDL, IDL, VLDL remnants, and Lp(a). The simple way to think about it is this: **Higher ApoB usually means more atherogenic particles are circulating.** But this is where people often stop too early. The real question is not just: **“Is my ApoB high?”** The better question is: **“Why is my ApoB high?”** Because two people can have the exact same ApoB level for completely different biological reasons. One person may have a strong genetic tendency and reduced LDL-receptor activity. Another may have insulin resistance and increased VLDL production from the liver. Another may have hypothyroidism slowing particle clearance. Another may be a lean person eating a very-low-carbohydrate diet and experiencing a large increase in LDL and ApoB despite low triglycerides and otherwise good metabolic markers. Another may be actively losing weight and temporarily mobilizing more fat. Another may have very high Lp(a), kidney disease, hormonal changes, diabetes, or a medication effect. That is why one number by itself never tells the whole story. **The pattern matters.** There are really two major ways ApoB rises: **1. You are producing more ApoB-containing particles.** The liver produces VLDL particles, and each of those particles carries one ApoB molecule. As VLDL is metabolized, it can become IDL and ultimately LDL. If the liver is producing more particles, ApoB can rise. This is often seen in people with insulin resistance, poor glucose control, metabolic syndrome, and increased hepatic fat production. **2. You are clearing the particles too slowly.** Your liver uses LDL receptors to remove ApoB-containing particles from circulation. If those receptors are reduced or less active, the particles stay in the blood longer. That can happen with genetics, hypothyroidism, certain dietary responses, hormonal changes, and other conditions.

Hi everyone, A quick update on the Weekly Live Classes. From now on, all Live class recordings will be posted under the lesson category called “Weekly Live Classes.” I’m also moving the previous Live recordings into that section, and more are being added daily until everything is organized in one place. We are also opening parts of the Skool community to the public so new members can get a small taste of what the community is about. They may be able to see that certain videos, lessons, and Live recordings exist, but they will not be able to access the full content unless they are a paid member. This gives new people a chance to explore the community while keeping the full lessons, Live classes, Q&A, and deeper education reserved for our paid members. If you are looking for a past Live, check Classroom → Weekly Live Classes. Thank you for being part of the community. Maurice Daher, CNS Eat Based On Your Biology, Not Ideology™

Hi @Wei Huang and @Maurice Daher I'm kinda create a post in here so people see who is interested for the Pomegranate we are talking about during our session. I'm so in for this and thanks to Wei for volunteering to deliver for us. Please everyone comment below to those are interested 👇 so Maurice would know how much to charge us each.