Glucose.... and Happy Valentines day
Since its valentines day I think its the perfect time to talk about the heart, blood, and the sugary treats we are about to indulge in... The flatter your blood glucose curve, the slower you age...this is one of the most powerful, controllable levers for longevity, as supported by research showing that glucose variability (especially after meals) predicts higher risks of cardiovascular disease, mortality, oxidative stress, inflammation, and accelerated aging more than average levels like HbA1c alone. Studies link higher glycemic variability to increased all-cause mortality, functional decline, and even longevity markers in centenarians, where stable, lower glucose fluctuations correlate with better outcomes (e.g., https://pmc.ncbi.nlm.nih.gov/articles/PMC10442283/; https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.955101/full As some who is obsessed with education on anti-aging, here's the evidence-based toolkit to flatten your curve and shift your body into repair mode (less mTOR/growth, more AMPK/autophagy): - Eat in the right order (fiber/veggies first, then protein/fats, carbs last). This creates a "mesh" in the stomach, slashing post-meal spikes and insulin levels without changing what you eat; multiple studies confirm veggies/protein preloading dramatically blunts glucose response (e.g., https://www.uclahealth.org/news/article/eating-certain-order-helps-control-blood-glucose). - Add vinegar (e.g., 1-2 tbsp apple cider vinegar in water before/ with carb-heavy meals). Acetic acid slows carb absorption and reduces spikes significantly; reviews show benefits with as little as 15mL daily (e.g., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243436/).